Evidence map›Paper›PMID 40926611›Full record

ReviewMini reviews in medicinal chemistry2025

Recent Development of CXCR4-Targeted Nuclear Medicine Research in Adrenocortical Tumors.

Ming Wang, Qiusong Chen, Shaobo Yao, Haonan Yu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mini reviews in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ming WangDepartment of PET/CT Diagnostic Imaging, Tianjin Medical University General Hospital, Tianjin 300052, China.
Qiusong ChenDepartment of PET/CT Diagnostic Imaging, Tianjin Medical University General Hospital, Tianjin 300052, China.
Shaobo YaoDepartment of PET/CT Diagnostic Imaging, Tianjin Medical University General Hospital, Tianjin 300052, China.
Haonan YuDepartment of PET/CT Diagnostic Imaging, Tianjin Medical University General Hospital, Tianjin 300052, China.

Funding

Joint Funds for the Innovation of Science and Technology, Fujian Province 2024Y9138National Natural Science Foundation of China 82171982Natural Science Foundation of Fujian Province 2023J06031
6 · The paper itself

Abstract

The diagnosis of adrenocortical tumors remains clinically challenging due to overlapping morphological and functional features between benign, malignant, and hormonally active lesions. Malignant and functional tumors are frequently associated with poor prognosis. Traditional morphological imaging methods, such as CT and MRI, cannot reliably distinguish lesion types. Recent evidence suggests that molecular imaging targeting C-X-C motif chemokine receptor 4 (CXCR4), a biomarker overexpressed in functional adenomas and adrenocortical carcinomas (ACC), offers enhanced diagnostic precision. For instance,

Indexed as

Adrenal Cortex NeoplasmsNuclear MedicineRadiopharmaceuticalsReceptors, CXCR4AnimalsHumansCXCR4 protein, humanRadiopharmaceuticalsReceptors, CXCR4adrenocortical carcinomasAdrenocortical tumorsCushing's syndromeCXCR4pentixaforPET.primary aldosteronism

Identifiers

PMID40926611

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.