Trial reportJournal of dental research2026
Randomized Clinical Trial on Caries Prevention of Silver Diamine Fluoride.
Trial report in Journal of dental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Effects of graded prevention intervention combined with minimally invasive restoration on the oral health trajectory of caries-susceptible children.Frontiers in public health · 2026Trial
- Silver Diamine Fluoride in Oral Health Policy: A Strategic Pathway to Improve Access and Equity.Journal of public health dentistry · 2026Article
- Comparative Efficacy of Silver Diamine Fluoride and Sodium Fluoride in Managing Early Childhood Caries: An Updated Systematic Review and Meta-Analysis.International journal of dentistry · 2026Review
- Effect of silver diamine fluoride versus fluoride varnish in arresting early childhood caries: A clinical study.Bioinformation · 2026Article
- Is silver diamine fluoride more effective than sodium fluoride varnish at preventing caries in upper anterior primary teeth?Evidence-based dentistry · 2025Article
- Early Childhood Caries and Its Associated Factors Among 5-Year-Old Children in Shenzhen City, China: A Cross-Sectional Study.Dentistry journal · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This 30-mo double-blind randomized clinical superiority trial aimed to assess the effectiveness of semiannual application of 38% silver diamine fluoride (SDF) solution in preventing early childhood caries in primary upper anterior teeth. The active comparator was 5% sodium fluoride varnish (FV). The primary outcome was the mean number of new carious tooth surfaces per child at the 30-mo follow-up. Children aged 3 to 4 y were block randomized to receive semiannual application of SDF or FV on their primary upper anterior teeth over a 30-mo period in kindergarten. Parents completed a validated questionnaire to collect information on child oral health-related behaviors and sociodemographic characteristics. In an intention-to-treat analysis, multilevel logistic regression with a generalized estimating equation (GEE) model was performed. At baseline, 730 children with 17,480 sound tooth surfaces were recruited (SDF group,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.