ArticleJournal of the Chinese Medical Association : JCMA2025
Cardiac magnetic resonance parameters for prognostic stratification in pulmonary hypertension: A longitudinal study.
Article in Journal of the Chinese Medical Association : JCMA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiac magnetic resonance (CMR) imaging is a critical tool for the diagnosis and evaluation of pulmonary hypertension (PH). This study aimed to investigate the temporal changes in cardiac morphological and functional characteristics in PH using CMR, with the goal of identifying early indicators of adverse clinical outcomes.
methodsThis retrospective study included patients diagnosed with PH using right heart catheterization. Each patient underwent two CMR sessions, approximately 1.5 years apart, for follow-up. CMR characteristics, including morphological and functional parameters such as myocardial strain, were analyzed in relation to the primary adverse events endpoint, defined as a composite of heart failure hospitalization and all-cause mortality.
resultsA total of 36 patients (8 men and 28 women, mean age 48.0 ± 13.3 years) were enrolled. Eleven patients (30.6%) experienced adverse events after the second CMR. High right ventricular (RV) volume and worse RV strain at follow-up were observed in patients who experienced future events (RV end-diastolic volume [RVEDV], 247.2 vs 182.3 mL, p = 0.029; and right ventricular global longitudinal strain [RVGLS], -12.0% vs -17.1%, p = 0.021, respectively). In contrast, an increase in left ventricular ejection fraction (LVEF) and left ventricular (LV) volume was noted in patients without events, whereas a decrease in LV end-diastolic volume was associated with subsequent events (111.6 vs 123.9 mL, p = 0.024). An increase in LVEF was observed in patients without events (61.5% vs 57.3%, p = 0.030), underscoring the predictive value of LV function.
conclusionThis study emphasizes the value of CMR in monitoring patients with PH, particularly for assessing ventricular function as a predictor of future outcomes. The observed trends in myocardial strain highlight its potential as a prognostic marker, warranting further research to confirm its clinical utility.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.