Evidence map›Paper›PMID 40925940›Full record

ReviewJournal of perinatology : official journal of the California Perinatal Association2025

Meconium obstruction of prematurity in tiny babies - towards developing an international consensus.

Graeme J Pitcher, Akio Kubota, Noelle E Younge, Christoph Bührer, C Michael Cotten, Katrin Mehler, Timothy J Boly, Riad Rahhal, Satoshi Kusuda, Matthew A Rysavy and 1 more

Abstract readReview
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In one paragraph

Review in Journal of perinatology : official journal of the California Perinatal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Graeme J PitcherUniversity of Iowa Stead Family Children's Hospital, Iowa City, IA, USA. graeme-pitcher@uiowa.edu.ORCID http://orcid.org/0000-0003-1908-6900
Akio KubotaWakayama Medical University, Wakayama City, Wakayama, Japan.
Noelle E YoungeDuke University School of Medicine, Durham, NC, USA.
Christoph BührerUniversity Hospital Charite Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0002-9950-414X
C Michael CottenDuke University School of Medicine, Durham, NC, USA.
Katrin MehlerUniversity Hospital Cologne, Cologne, Germany.
Timothy J BolyUniversity of Iowa Stead Family Children's Hospital, Iowa City, IA, USA.ORCID http://orcid.org/0000-0002-8892-8086
Riad RahhalUniversity of Iowa Stead Family Children's Hospital, Iowa City, IA, USA.
Satoshi KusudaTokyo Healthcare University, Neonatal Research Network of Japan, Kyorin University, Tokyo, Japan.ORCID http://orcid.org/0000-0001-5318-8877
Matthew A RysavyMcGovern Medical School at McGovern Medical School at UTHealth Houston, Houston, TX, USA.ORCID http://orcid.org/0000-0002-1209-6607
Tiny Baby Collaborative Steering Committee

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal perforation occurring in extremely low gestational age neonates is a devastating complication, associated with high mortality and morbidity. Multiple phenotypes of bowel perforation in premature infants have been described, with the most common being spontaneous, or isolated, intestinal perforation and perforated necrotizing enterocolitis. The purpose of this article is to summarize literature describing "meconium obstruction of prematurity", increasingly recognized as a distinct clinical phenotype in the smallest and most immature neonates. The goal of this review is to improve international recognition and understanding of this high-risk clinical condition. The lack of standardized nomenclature has been an obstacle to progress in understanding, preventing, and treating this important and more frequently encountered condition. The recognition of meconium obstruction requiring medical or surgical management is a clear distinguishing factor from other bowel pathologies of prematurity.

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.