Evidence map›Paper›PMID 40925912›Full record

ArticleCommunications biology2025

Anatomical circuits for flexible spatial mapping by single neurons in posterior parietal cortex.

Bashir Ahmed, Hee-Kyoung Ko, Maria Rüsseler, Jackson E T Smith, Kristine Krug

Abstract read
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A hemispheric decoding principle for vestibular heading perception in the posterior sylvian area.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. The Richness of Vision in the Mammalian Brain: Neural Codes for Visual Perception and Behavior in Three Dimensions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bashir AhmedDepartment of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-9989-2659
Hee-Kyoung KoDepartment of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.
Maria RüsselerDepartment of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.
Jackson E T SmithDepartment of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.
Kristine KrugDepartment of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK. kristine.krug@ovgu.de.ORCID http://orcid.org/0000-0001-7119-9350

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) 406269671Deutsche Forschungsgemeinschaft (German Research Foundation) 425899996Deutsche Forschungsgemeinschaft (German Research Foundation) 507082410RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/H016902/1Royal Society University Research FellowshipWellcome TrustWellcome Trust (Wellcome) 101092/Z/13/Z
6 · The paper itself

Abstract

Primate lateral intraparietal area (LIP) has been directly linked to perceptual categorization and decision-making. However, the intrinsic LIP circuitry that gives rise to the flexible generation of motor responses to sensory instruction remains unclear. Using retrograde tracers, we delineate two distinct operational compartments based on different intrinsic connectivity patterns of dorsal and ventral LIP. These connections form an anatomical loop with a sensory-like, point-to-point projection from ventral to dorsal LIP and an asymmetric, widespread projection in reverse. In neurophysiological recordings, LIP neurons exhibit motor response fields spatially distinct from their sensory receptive field. Different associations of motor response and receptive fields in single neurons tile visual space. Ventral LIP neurons tend to have motor response fields distant from their sensory receptive fields. This circuit provides the neural substrate to generate the dynamic processes for flexible allocation of attention and motor responses in response to salient or instructive visual input across the visual field.

Indexed as

Brain MappingNeuronsParietal LobeAnimalsMacaca mulattaMale

Identifiers

PMID40925912
PMCPMC12420791

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.