Trial reportThe American journal of clinical nutrition2025
Ingestion of a lipid-rich meat matrix blunts the postexercise increase of myofibrillar protein synthesis rates in healthy adults: a randomized controlled trial.
Trial report in The American journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05876299 (The Anabolic Properties of a Lipid-rich Pork Matrix), which is not on this map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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The Anabolic Properties of a Lipid-rich Pork Matrix
Who cites it
2 citing papers in PubMed.
- Complementary plant protein pairing does not further increase postexercise myofibrillar protein synthesis after a 20 g protein dose within a high-carbohydrate whole-food matrix in young adults: a randomized controlled trial.The American journal of clinical nutrition · 2026Trial
- Food and Medicine Homology Substances as Potential Modulators of the Gut-Muscle Axis in Animal Meat Quality: A Review.Foods (Basel, Switzerland) · 2026Review
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is considerable variation in the anabolic action of ingesting protein-dense foods on the stimulation of postprandial myofibrillar protein synthesis rates (MPS) despite ingesting similar amounts of protein and essential amino acids (EAA).
objectivesThis study aims to determine the effects of consuming high-fat pork (HFP), low-fat pork (LFP), or a carbohydrate control (CHO) on the MPS response.
methodsIn a semicrossover design, 16 physically active adults (25 ± 5 y; 25.0 ± 2.3 kg/m
resultsBoth HFP and LFP conditions increased MPS above postabsorptive values (P = 0.028 and P < 0.001, respectively), with LFP eliciting a greater postexercise MPS {0.106 ± 0.026 %/h [95% confidence interval (CI): 0.088, 0.118]} than HFP [0.072 ± 0.027 %/h (95% CI: 0.057, 0.087); P = 0.030] and CHO [0.056 ± 0.035 %/h (95% CI: 0.41, 0.71); P < 0.001]. The absolute change in MPS from basal was significantly correlated with peak EAA and leucine concentrations (r = 0.4638, P = 0.017; r = 0.4211, P = 0.032).
conclusionsLFP stimulated MPS more than HFP or CHO conditions. Our work demonstrated that other nutrients in the food matrix, beyond total ingested protein or EAAs, can impact the regulation of MPS in healthy adults. This trial was registered at clinicaltrials.gov as NCT05876299.
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