ArticleInternational journal of surgery case reports2025
Orbital invasion by an antrochoanal polyp in a factor V-deficient patient: A case report of diagnostic and surgical challenges.
Article in International journal of surgery case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAntrochoanal polyps (ACPs) typically extend posteriorly into the choana and nasopharynx; orbital invasion is exceptionally rare. This report details an atypical ACP with orbital extension in a coagulopathic patient, highlighting diagnostic and surgical complexities. CASE PRESENTATION: A 46-year-old woman with severe Factor V deficiency (0.8 %) presented with 2 years of progressive left nasal obstruction, rhinorrhea, headaches, and snoring. Examination revealed a left nasal polyp extending to the vestibule and bilateral turbinate hypertrophy. Coagulation profiles showed marked prolongation (PTT 126.8 s, INR 3.45). CT imaging identified a hypodense polyp originating from the left maxillary sinus, expanding through the infundibulum into the choana. Crucially, MRI confirmed orbital fossa invasion through bony dehiscence, with T2 hyperintensity and no gadolinium enhancement excluding malignancy. Histopathology post-functional endoscopic sinus surgery (FESS) demonstrated an inflammatory, angiomatous polyp featuring telangiectatic vasculature and stromal hemorrhage. DISCUSSION: Orbital extension likely resulted from chronic erosion of the lamina papyracea, exacerbated by mass effect. Angiomatous histology-uncommon in adults-and profound coagulopathy amplified bleeding risks. Multidisciplinary management (hematology/ENT) guided preoperative factor replacement and hypotensive anesthesia. Angled endoscopes facilitated precise dissection at the orbital interface, avoiding combined approaches (e.g., Caldwell-Luc) due to coagulopathy. This case underscores MRI's indispensability in delineating atypical extensions and the need for tailored techniques to ensure complete resection amid coagulopathies.
conclusionThis first reported orbital invasion by an ACP in a Factor V-deficient patient illustrates that benign polyps may erode critical boundaries under chronic pressure. Vigilance for aberrant extensions via advanced imaging, coupled with individualized surgical planning for coagulopathic patients, is essential to mitigate recurrence and complications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.