ReviewEmerging microbes & infections2025
Matrix protein 1 (M1) of influenza A virus: structural and functional insights.
Review in Emerging microbes & infections, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Global evolutionary landscape of H11 avian influenza and initial isolates identified in Xinjiang, China.Emerging microbes & infections · 2026Article
- NS-segment-based reporter influenza A viruses: engineering strategy, applications, and limitations.Journal of virology · 2026Review
- What Antibody Repertoires See: Structural and Immunogenetic Insights Into Influenza A Virus Hemagglutinin Recognition.Immunological reviews · 2026Review
- Article
- Protection AgainstPharmaceutics · 2026Article
- Influenza virus research in an era of emerging respiratory threats: host-virus interactions, surveillance technologies, antiviral management and resistance, and vaccine preparedness.Frontiers in microbiology · 2026Review
- Comparative progress on the mechanisms of airway mucosal injury induced by different pathogens: SARS-CoV-2, influenza A virus, and Mycoplasma pneumoniae.Frontiers in cellular and infection microbiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enveloped viruses rely on matrix proteins for structural integrity and lifecycle progression. Matrix protein 1 (M1) is the most abundant structural protein of influenza A virus (IAV), playing a multifaceted role in viral uncoating, polymerase activity, vRNA transcription and replication, and assembly and budding. The M1 protein not only interacts with host cells but also regulates viral morphogenesis, thereby influencing viral transmissibility and pathogenicity. These properties make it a highly promising antiviral target. This review elucidates the intricate structure and function of M1, highlighting its regulatory influence on IAV replication and adaptation, and providing critical insights into viral replication dynamics and epidemiological shifts. Beyond engaging host factors, the M1 protein orchestrates virion morphogenesis - thereby shaping viral transmissibility and pathogenicity-making it a highly attractive antiviral target.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.