Evidence map›Paper›PMID 40925056›Full record

ReviewBiomaterials2026

Wearable bioelectronics for skin cancer management.

Ganghao Liang, Songyue Chen, Jun Chen

Abstract readReview
In one paragraph

Review in Biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Bioelectronic Considerations in Biomedical Microneedles.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ganghao LiangDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Songyue ChenDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Jun ChenDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA. Electronic address: jun.chen@ucla.edu.

Funding

Magnetoelastic Vascular GraftsR01HL175135 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Jun Chen · 2025 to 2026
$1.1M
A soft magnetoelastic microneedle patch for rapid skin cancer screeningR01CA287326 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Jun Chen · 2024 to 2026
$1.1M
American Heart Association-American Stroke Association 23IPA1054908American Heart Association-American Stroke Association 23SCEFIA1157587American Heart Association-American Stroke Association 23TPA1141360NCI NIH HHS R01 CA287326NHLBI NIH HHS R01 HL175135
6 · The paper itself

Abstract

Wearable bioelectronics have transformed modern biomedical applications by enabling seamless integration with biological tissues, providing continuous, comprehensive, and personalized healthcare. Skin cancer, particularly melanoma, poses a significant clinical challenge due to its high metastatic potential and associated mortality. Traditional diagnostic approaches face limitations in accuracy, accessibility, and reproducibility, while existing treatments are often constrained by systemic toxicity and therapeutic resistance. Wearable bioelectronics offer innovative solutions for both diagnosis and treatment. Advanced platforms incorporating cutting-edge technologies optimize diagnostic accuracy and treatment precision. This review systematically examines the recent advancements in wearable bioelectronics for skin cancer management. Firstly, the pathological mechanisms underlying skin cancer is discussed. Next, we discuss the wearable optical and electrochemical sensing technologies for early and non-invasive cancer screening. We further evaluate wearable therapeutic platforms, for chemotherapy, photodynamic therapy, electrotherapy, and immunotherapy, along with combinatorial cancer treatment strategies. Key device attributes-including integration, mechanical properties, and biocompatibility-are analyzed to highlight their role in optimizing cancer treatment performance and patient compliance. Finally, we address major challenges, including technological bottlenecks and barriers to clinical translation, while proposing future research directions to enhance the applicability of wearable bioelectronics in precision oncology. By integrating interdisciplinary innovations, wearable devices have the potential to redefine skin cancer diagnosis and treatment, offering safer, more effective, and patient-centered solutions.

Indexed as

Skin NeoplasmsWearable Electronic DevicesAnimalsBiosensing TechniquesHumansDiagnosisMelanomaOcologySkin cancerTherapyWearable bioelectronics

Identifiers

PMID40925056
PMCPMC13046297

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.