Evidence map›Paper›PMID 40924751›Full record

ReviewPLoS neglected tropical diseases2025

Orthohantavirus rodent hosts and genotypes in Southern South America: A narrative review.

Natalia Ortiz, Juan Diego Pinotti, Verónica Andreo, Raúl Enrique González-Ittig, Cristina Noemí Gardenal

Abstract readReview
In one paragraph

Review in PLoS neglected tropical diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Natalia OrtizInstituto de Diversidad y Ecología Animal (IDEA), CONICET and Universidad Nacional de Córdoba, Córdoba, Córdoba, Argentina.
Juan Diego PinottiInstituto de Diversidad y Ecología Animal (IDEA), CONICET and Universidad Nacional de Córdoba, Córdoba, Córdoba, Argentina.ORCID 0000-0002-4673-5868
Verónica AndreoInstituto de Altos Estudios Espaciales Mario Gulich (CONAE-UNC), Falda del Cañete, Córdoba, Argentina.
Raúl Enrique González-IttigInstituto de Diversidad y Ecología Animal (IDEA), CONICET and Universidad Nacional de Córdoba, Córdoba, Córdoba, Argentina.
Cristina Noemí GardenalInstituto de Diversidad y Ecología Animal (IDEA), CONICET and Universidad Nacional de Córdoba, Córdoba, Córdoba, Argentina.

Funding

Agencia Nacional de Promoción Científica y Tecnológica, ArgentinaSecretaría de Ciencia y TecnologíaUniversidad Nacional de Córdoba
6 · The paper itself

Abstract

Orthohantaviruses, family Hantaviridae, are zoonotic agents that pose a significant public health threat, particularly in South America, where they cause severe respiratory illnesses in humans. Despite their importance, knowledge gaps remain regarding the distributions of both the viruses and their rodent hosts in Southern South America, a region characterized by a great complexity of viral genotypes and reservoirs. This review provides an updated overview of orthohantavirus hosts and their associated viral genotypes in Argentina, Chile, Paraguay, and Uruguay. Through an extensive literature review, we identified 14 rodent species that serve as reservoir hosts for 15 distinct orthohantavirus genotypes. These rodent hosts inhabit a variety of ecosystems, from forests and arid zones to grasslands and wetlands, and even modified or anthropized habitats, demonstrating a wide geographic and ecological range. Our findings highlight the diversity of orthohantaviruses in this region, reflecting their complex evolutionary histories. Maintaining an up-to-date knowledge base on this topic is essential for effective decision-making in public health.

Indexed as

Disease ReservoirsHantavirus InfectionsOrthohantavirusRodentiaAnimalsEcosystemGenotypeHumansPhylogenySouth America

Identifiers

PMID40924751
PMCPMC12419662

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.