Evidence map›Paper›PMID 40924438›Full record

ArticleInfection and immunity2025

Lymphotoxin beta receptor

Marcel Helle, Ursula R Sorg, Johannes Ptok, Rachel E Thomas, Katharina Pracht, Patrick Petzsch, Alain de Bruin, Hans-Martin Jäck, Karl Köhrer, Daniel Degrandi and 1 more

Abstract read
In one paragraph

Article in Infection and immunity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marcel HelleInstitute of Medical Microbiology and Hospital Hygiene, Heinrich Heine University, Düsseldorf, Germany.ORCID 0009-0000-5656-3230
Ursula R SorgInstitute of Medical Microbiology and Hospital Hygiene, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0002-0641-6117
Johannes PtokInstitute of Virology, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0002-0322-5649
Rachel E ThomasDepartment Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Katharina PrachtDivision of Molecular Immunology, Department of Medicine 3-Rheumatology and Immunology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, , Erlangen, Germany.ORCID 0000-0002-8943-4897
Patrick PetzschGenomics and Transcriptomics Laboratory, Biological and Medical Research Centre (BMFZ), Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0002-8355-5524
Alain de BruinDepartment Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Hans-Martin JäckDivision of Molecular Immunology, Department of Medicine 3-Rheumatology and Immunology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, , Erlangen, Germany.
Karl KöhrerGenomics and Transcriptomics Laboratory, Biological and Medical Research Centre (BMFZ), Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0003-3644-2022
Daniel DegrandiInstitute of Medical Microbiology and Hospital Hygiene, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0001-6281-0357
Klaus PfefferInstitute of Medical Microbiology and Hospital Hygiene, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0002-5652-6330

Funding

Bundesministerium für Bildung und Forschung 01KX2021Jürgen Manchot Stiftung
6 · The paper itself

Abstract

Lymphotoxin β receptor (LTβR/TNFRSF3) signaling plays a crucial role in immune defense. Notably, LTβR-deficient (LTβR

Indexed as

B-LymphocytesBone MarrowLymphotoxin beta ReceptorPeritoneal CavityT-Lymphocyte SubsetsToxoplasmaToxoplasmosisAnimalsMiceMice, Inbred C57BLMice, KnockoutSignal TransductionLymphotoxin beta Receptoradaptive immunityB-1 cellsB cellsbone marrowlymphotoxin beta receptorperitoneal cavityToxoplasma gondii

Identifiers

PMID40924438
PMCPMC12519803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.