ArticleOdontology2026
Three-dimensional evaluation of age-related changes in root canal curvature and dentin thickness in mandibular first molars using micro-computed tomography.
Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to investigate the age-related alterations in mesial roots of mandibular first molar in terms of root canal curvature values, dentin thickness, interorifice distance, deviation from apical foramen, and location of apical foramen using a three-dimensional curvature measurement method and micro-computed tomography (micro-CT). Forty-five mesial roots of mandibular first molars from three age groups (Group 1: ≤ 30 years, Group 2: 31-59 years, Group 3: ≥ 60 years) were scanned using micro-CT. The central axis of each mesiobuccal and mesiolingual canal was analyzed using cubic B-spline curves to calculate canal curvature. Dentin thickness, deviation of apical foramen from the anatomical apex, and the location of apical foramen in mesiobuccal and mesiolingual canals were measured and recorded. Statistical analyses, including one-way ANOVA, Mann-Whitney U, Kruskal-Wallis and Pearson's correlation tests, were performed to assess age-related differences in curvature, interorifice distance, and dentin thickness with a 5% significance threshold. No statistically significant differences in root canal curvature were observed across the three age groups (p > .05), although a slight increase in curvature was noted in Group 3. Interorifice distance was significantly lower in Group 2 (p < .05), but no significant relationship was found between mesiobuccal curvature and interorifice distance. Dentin thickness, however, showed significant variations: Groups 1 and 2 exhibited thinner mesial dentin (2-6 mm levels), while Group 3 demonstrated greater distal dentin thickness (5-8 mm levels) (p < .05). Apical foramen location and deviation remained consistent across age groups (p > .05), predominantly situated centrally on the root surface. While root canal curvature did not vary significantly with age (p > .05), dentin thickness showed notable age-related differences (p < .05). A significant correlation was observed between the mesiolingual canal curvature and interorifice distance, but no such correlation was found for the mesiobuccal canal. A significant age-related increase in dentin thickness in both the mesiobuccal and mesiolingual canals underscores the impact of secondary dentin deposition, which is probably uniform as the root canal curvature seems to remain relatively stable across the lifespan in mandibular first molars.
Indexed as
Identifiers
40924341What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.