Evidence map›Paper›PMID 40924338›Full record

ArticleIn vitro cellular & developmental biology. Animal2025

The ability of the polysaccharide extract Cissus sicyoides L. leaves to maintain normal follicle structure in ovarian tissue culture.

Camila Maria Araújo de Aguiar, Solano Dantas Martins, Alesandro Silva Ferreira, Hyandra Emilly Oliveira Santos-Saboia, João Eudes Farias Cavalcante-Filho, Maria Alice Felipe Oliveira, Maria Joana Nogueira de Moura, Rafael Aires Lessa, Maria Gonçalves Pereira, Cibele Dos Santos Borges and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in In vitro cellular & developmental biology. Animal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. International journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Camila Maria Araújo de AguiarPostgraduate Program in Physiological Sciences (PPGCF), State University of Ceará (UECE), Fortaleza, CE, Brazil.ORCID http://orcid.org/0000-0001-6560-0160
Solano Dantas MartinsLaboratory of Research in Reproductive Physiology (FisioRep Lab), Parnaíba Delta Federal University (UFDPar), Av. São Sebastião, 2819, Campus Ministro Reis Velloso, Parnaíba, PI, Brazil.ORCID http://orcid.org/0000-0002-0554-5283
Alesandro Silva FerreiraLaboratory of Research in Reproductive Physiology (FisioRep Lab), Parnaíba Delta Federal University (UFDPar), Av. São Sebastião, 2819, Campus Ministro Reis Velloso, Parnaíba, PI, Brazil.ORCID http://orcid.org/0000-0002-2854-1891
Hyandra Emilly Oliveira Santos-SaboiaPostgraduate Program in Physiological Sciences (PPGCF), State University of Ceará (UECE), Fortaleza, CE, Brazil.ORCID http://orcid.org/0009-0006-1549-5925
João Eudes Farias Cavalcante-FilhoLaboratory of Research in Reproductive Physiology (FisioRep Lab), Parnaíba Delta Federal University (UFDPar), Av. São Sebastião, 2819, Campus Ministro Reis Velloso, Parnaíba, PI, Brazil.ORCID http://orcid.org/0000-0001-5009-9561
Maria Alice Felipe OliveiraPostgraduate Program in Physiological Sciences (PPGCF), State University of Ceará (UECE), Fortaleza, CE, Brazil.ORCID http://orcid.org/0000-0003-2349-2194
Maria Joana Nogueira de MouraMulticenter Graduate Program in Biochemistry and Molecular Biology (PMBqBM), State University of Rio Grande do Norte (UERN), Mossoró, RN, Brazil.ORCID http://orcid.org/0000-0003-0328-3635
Rafael Aires LessaLaboratory of Bioactive Polysaccharides (LAPOBIO), Faculty of Education, Sciences and Letters of Sertão Central (FECLESC), State University of Ceará (UECE), Quixadá, CE, Brazil.ORCID http://orcid.org/0009-0009-4028-8110
Maria Gonçalves PereiraLaboratory of Bioactive Polysaccharides (LAPOBIO), Faculty of Education, Sciences and Letters of Sertão Central (FECLESC), State University of Ceará (UECE), Quixadá, CE, Brazil.ORCID http://orcid.org/0000-0003-1699-6415
Cibele Dos Santos BorgesLaboratory of Tissue Biology and Developmental Toxicology (BioTox), Department of Bioscience, Biological and Health Sciences Center (CCBS), Federal University of the Semi-Arid Region (UFERSA), Mossoró, RN, Brazil.ORCID http://orcid.org/0000-0003-3711-811X
Vânia Marilande CeccattoLaboratory of Biochemistry and Gene Expression (LABIEX), Higher Institute of Biomedical Sciences (ISCB), State University of Ceará (UECE), Fortaleza, CE, Brazil.ORCID http://orcid.org/0000-0003-4839-4400
Sônia Nair BáoMicroscopy and Microanalysis Laboratory, Department of Cell Biology, Institute of Biological Sciences, University of Brasília, Brasília, Brazil.ORCID http://orcid.org/0000-0002-9873-3098
Valdevane Rocha AraújoPostgraduate Program in Physiological Sciences (PPGCF), State University of Ceará (UECE), Fortaleza, CE, Brazil. fisioreplab@ufdpar.edu.br.ORCID http://orcid.org/0000-0003-3984-2099

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 407992/2021-9
6 · The paper itself

Abstract

The present study aimed to (1) evaluate the effects of different concentrations of the polysaccharide extract of Cissus sicyoides (PE-Cs) during in vitro culture of preantral follicles included in goat ovarian tissue on (i) follicular morphology and activation, (ii) ovarian stromal density, (iii) follicular and oocyte diameters, (iv) antioxidant enzymes activity (SOD, CAT, and GPx), (v) quantification of MDA, thiol, and nitrite levels; as well as to (2) measure the total antioxidant capacity of the extract. The ovarian cortex fragments were cultured at 39 °C in a humidified atmosphere with 5% CO

Indexed as

Ovarian FollicleOvaryPlant ExtractsPlant LeavesPolysaccharidesTissue Culture TechniquesAnimalsAntioxidantsFemaleGoatsOocytesAntioxidantsPlant ExtractsPolysaccharidesAntioxidantCissus sicyoidesIn situPreantral folliclesVegetable insulin

Identifiers

PMID40924338

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.