Evidence map›Paper›PMID 40924284›Full record

ArticleInternational journal of clinical pharmacy2026

Experiences and challenges of implementing clinical medication reviews in daily practice: a mixed-methods study.

Sek Hung Chau, Petra J M Elders, Jacintha Domić, H J Marjorie G Nelissen-Vrancken, François G Schellevis, Jacqueline G Hugtenburg

Abstract read
In one paragraph

Article in International journal of clinical pharmacy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sek Hung ChauDepartment of Clinical Pharmacology and Pharmacy, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands. s.chau@amsterdamumc.nl.ORCID http://orcid.org/0000-0002-0690-5009
Petra J M EldersAmsterdam Public Health, Quality of Care, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-5907-7219
Jacintha DomićDepartment of Clinical Pharmacology and Pharmacy, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-7550-7055
H J Marjorie G Nelissen-VranckenDutch Institute for Rational Use of Medicine, Utrecht, The Netherlands.
François G SchellevisAmsterdam Public Health, Quality of Care, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-9745-6394
Jacqueline G HugtenburgDepartment of Clinical Pharmacology and Pharmacy, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-6098-2438

Funding

ZonMw 1131020031
6 · The paper itself

Abstract

introductionOrganisational problems still prevent widespread implementation of clinical medication reviews. The Opti-Med2 method was developed to facilitate the process of performing clinical medication reviews. The method includes patient involvement by means of a questionnaire and expert teams of community pharmacists and general practitioners (GPs) to perform pharmacotherapeutic analyses, providing the patients' own GP with pharmacotherapeutic advice. There is a supporting role of community pharmacy technicians and general practice nurses/assistants in the process.

aimTo gain insight into the implementation of the Opti-Med2 method within the framework of pharmacotherapeutic audit meeting groups in the Netherlands.

methodA mixed-methods implementation study in seven groups of primary care healthcare providers. Quantitative data were collected using study forms. Semi-structured interviews with 8 GPs, 5 community pharmacists and 2 community pharmacy technicians were held. Interviews were transcribed verbatim and were analysed using the extended Normalization Process Theory.

resultsOnly one group provided sufficient quantitative data for analysis. Of the pharmacotherapeutic advice given by the expert team, 72% was adopted by the GPs of which 85% resulted in an intervention with the patient. In general, the healthcare providers were satisfied with using the Opti-Med2 method. The use of expert teams was appreciated by most GPs and community pharmacists. All healthcare providers were very satisfied with the use of the patient questionnaire.

conclusionAlthough full implementation of Opti-Med2 method as a whole was not achieved, the structured organisation of conducting CMRs and the use of questionnaires was deemed successful.

Indexed as

Community Pharmacy ServicesMedication Therapy ManagementFemaleGeneral PractitionersHumansMaleNetherlandsPharmacistsPharmacy TechniciansPrimary Health CareProfessional RoleSurveys and QuestionnairesAgedCommunity pharmacy servicesGeneral practitionersMedication reviewPatient participationPharmacistPharmacy technicians

Identifiers

PMID40924284
PMCPMC12992465

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.