ArticleVeterinary research communications2025
Dietary Nigella sativa oil confers protection against diazinon toxicity in nile tilapia (Oreochromis niloticus): A detoxification-based approach.
Article in Veterinary research communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Innovative Field Applications of Probiotics, Prebiotics, and Medicinal Plant Products for Disease Control in Aquaculture.Journal of fish diseases · 2026Review
- From traditional histopathology to virtual staining: deep learning approaches for assessing tissue lesions in farmed fish.Veterinary research communications · 2026Review
- Nanotechnology-Based Immunostimulants in Aquaculture: Mechanisms, Advances and Practical Applications.Veterinary medicine and science · 2026Review
- Dietary banana peels modulate waterborne oxyfluorfen-induced hepatotoxicity in Nile tilapia (Oreochromis niloticus) via regulation of redox homeostasis and ER stress signaling.Veterinary research communications · 2026Article
- Physiological Responses in the Hepatopancreas ofAntioxidants (Basel, Switzerland) · 2026Article
- Toxic effects of MPs and Up GradeVeterinary research communications · 2026Article
- Nigella sativa oil ameliorates malathion-ınduced toxicity in Nile tilapia: a multi-systemic and molecular evaluation.Fish physiology and biochemistry · 2026Article
- Nutritional detoxification strategies in aquaculture: bioactive feed additives mitigating oxidative stress and xenobiotic toxicity in fish.Fish physiology and biochemistry · 2026Review
- Omics technologies in aquafeed: unlocking the black box towards systems biology.Functional & integrative genomics · 2026Review
- Ameliorative Role of EthanolicVeterinary medicine international · 2026Article
- Medicinal and Aromatic Plant Oils in Aquafeeds: Mechanistic Perspectives on Growth Promotion, Immunomodulation, and Stress Resilience.Aquaculture nutrition · 2026Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study evaluated how dietary black seed oil (Nigella sativa L.) against the diazinon waterborne toxicity on Nile tilapia (Oreochromis niloticus), focusing on growth performance, hematological and biochemical parameters as well as oxidative stress markers and histological changes. A 40-day feeding trial was carried out using four experimental groups: Group 1 (control group), Group 2 (N. sativa-supplemented group), Group 3 (diazinon-exposed group), and Group 4 (diazinon-exposed with N. sativa supplementation group). The LC₅₀ value of diazinon for Nile tilapia was determined to be 4.642 mg/L, and fish were exposed to a sublethal concentration of LC₅₀/20 during the trial. Results demonstrated that diazinon exposure significantly impaired growth, hematological parameters, and liver function while increasing oxidative stress and tissue damage. Conversely, dietary supplementation with N. sativa oil significantly mitigated these adverse effects by enhancing specific growth rate, restoring RBC, Hb, and Hct values, improving liver enzyme profiles, and increasing antioxidant enzyme activity (SOD, CAT, GPx). Histological examinations confirmed that N. sativa oil reduced diazinon-induced damage in gill and liver tissues. The results show that N. sativa oil can be used as a functional feed ingredient to enhance fish resistance to chemical stressors that are commonly found in intensive aquaculture.
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