ArticleWorld journal of urology2025
Management of renal cancer with inferior vena cava extension over 30 years: a bi-centric study.
Article in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn 5-10% of cases, renal cancer extends into the venous system, particularly the inferior vena cava (IVC), which worsens prognosis. This study aims to assess morbidity, mortality, and oncological outcomes of patients treated surgically for renal cancer with IVC extension over a 30-year period, in two experienced centers. MATERIALS AND
methodsThis bicentric, retrospective study analyzed patients treated between 1988 and 2020 for renal cancer involving the IVC. Surgical approach varied based on thrombus level, with CPB mostly employed for thrombi above the hepatic veins.
resultsFrom 1988 to 2020, 213 patients were treated. Thrombi below the hepatic veins were found in 137 patients (64.3%), while 76 (35.7%) had thrombi above the hepatic veins. Synchronous metastases were identified in 34.3%. Median blood loss was 1.75 L. Transfusions were required in 81.8%.CPB use significantly extended hospital stay (p < 0.001) and increased complication rates (p < 0.01). Morbidity was recorded in 53% of patients. Postoperative mortality within 30 days occurred in 9.4% of cases. Median follow-up was 25 months. The 2- and 5-year OS rates were 50.2% and 29.6%, respectively. In multivariate analysis, M + and pN + status at diagnosis were the primaries prognostics factors for OS (HR = 1.54, p = 0.033 and HR = 2.21, p = 0.002). The 2 and 5 years PFS were 25.3% and 11.7%, respectively.
conclusionRenal cancer with IVC extension remains a highly aggressive disease with poor prognosis. While surgery offers a potential cure for some patients, the high rates of perioperative morbidity and mortality remain a challenge.
Indexed as
Identifiers
40924192What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.