Evidence map›Paper›PMID 40924185›Full record

ArticleJournal of cancer research and clinical oncology2025

Impact of sociodemographic and socioeconomic factors on functional and health-related quality of life outcomes 24 months after radical prostatectomy.

M Maas, K Funk, V Stühler, S Walz, H Bahlburg, J Hennenlotter, J Bedke, S Aufderklamm, A Stenzl, I Tsaur and 1 more

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Article in Journal of cancer research and clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

11 authors.

M MaasDepartment of Urology, University Hospital Tübingen, Eberhard Karls University, Hoppe-Seyler Str. 3, 72076, Tübingen, Germany.
K FunkDepartment of Urology, University Hospital Tübingen, Eberhard Karls University, Hoppe-Seyler Str. 3, 72076, Tübingen, Germany.
V StühlerDepartment of Urology, University Hospital Tübingen, Eberhard Karls University, Hoppe-Seyler Str. 3, 72076, Tübingen, Germany.
S WalzDepartment of Urology, University Hospital Tübingen, Eberhard Karls University, Hoppe-Seyler Str. 3, 72076, Tübingen, Germany.
H BahlburgDepartment of Urology, Marien Hospital Herne, Ruhr-University Bochum, Herne, Germany.
J HennenlotterDepartment of Urology, University Hospital Tübingen, Eberhard Karls University, Hoppe-Seyler Str. 3, 72076, Tübingen, Germany.
J BedkeDepartment of Urology, University Hospital Tübingen, Eberhard Karls University, Hoppe-Seyler Str. 3, 72076, Tübingen, Germany.
S AufderklammDepartment of Urology, University Hospital Tübingen, Eberhard Karls University, Hoppe-Seyler Str. 3, 72076, Tübingen, Germany.
A StenzlDepartment of Urology, University Hospital Tübingen, Eberhard Karls University, Hoppe-Seyler Str. 3, 72076, Tübingen, Germany.
I TsaurDepartment of Urology, University Hospital Tübingen, Eberhard Karls University, Hoppe-Seyler Str. 3, 72076, Tübingen, Germany.
Steffen RauschDepartment of Urology, University Hospital Tübingen, Eberhard Karls University, Hoppe-Seyler Str. 3, 72076, Tübingen, Germany. Steffen.rausch@med.uni-tuebingen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION AND

objectivesHigh socioeconomic status (SES) is associated with improved oncological outcomes across various cancer types, including prostate cancer. However, limited evidence exists regarding the impact of SES and lifestyle factors on patient-reported outcomes (PROs), including quality of life (QoL), health status (HS), and functional recovery following radical prostatectomy (RP). MATERIALS AND

methodsWe conducted a retrospective single-center analysis of 327 patients undergoing RP (177 open, 150 robotic-assisted) assessing pre- and postoperative functional outcomes (QoL, HS, erectile function, continence). PROs were evaluated 24 months postoperatively. Correlations with sociodemographic, socioeconomic (ISEI-based SES, marital status, occupational status, hometown size), and lifestyle factors (physical activity, BMI, mental stress) were analyzed.

resultsPathological features of locally advanced tumors correlated negatively with QoL and HS. Higher SES was significantly associated with improved continence, but not with QoL, HS, or erectile function. Pre-existing mental stress negatively affected both continence and HS. Regular physical activity correlated positively with QoL and HS. Multivariable regression confirmed these findings and identified mental stress, SES, partnership and physical activity as independent predictors of PROs.

conclusionBeyond adverse tumor pathology, mental stress adversely impacts functional recovery and subjective health. In contrast, physical activity and a stable partnership correlate with better PROs. These findings may inform personalized patient counseling to increase postoperative satisfaction.

Indexed as

ProstatectomyProstatic NeoplasmsQuality of LifeAgedHealth StatusHumansMaleMiddle AgedPatient Reported Outcome MeasuresRetrospective StudiesSocioeconomic FactorsHealth-related quality of life (HRQoL)Patient-reported outcomes (PROs)Psychosocial determinantsRadical prostatectomySocioeconomic status (SES)

Identifiers

PMID40924185
PMCPMC12420561

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.