ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2025
"Characterization of visual function parameters in relation to macular pigment optical density in a pediatric population".
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo analyze the relationship between various visual function parameters (refractive status, visual acuity and contrast sensitivity) and macular pigment optical density (MPOD) values, as well as dietary intake of lutein and zeaxanthin in a pediatric population.
methodsThirty-six healthy White pediatric patients participated in this cross-sectional study conducted at the Optometry Clinic (Faculty of Pharmacy, Seville, Spain). MPOD values were measured using the MPSII
resultsThe mean age of participants was 7.67 ± 1.21 years. MPOD values were similar between the right eye (0.51 ± 0.16 du) and the left eye (0.47 ± 0.23 du), with no statistically significant difference observed (p = 0.51). Visual acuity in both eyes ranged from - 0.08 to 0.10 logMAR (logarithm of the minimum angle of resolution). Contrast sensitivity was assessed at spatial frequencies of 1.5, 3, 6, 12 and 18 cycles per degree for each eye. No significant interocular differences were found for any of the visual parameters evaluated. All children in the study had medium or high adherence to the Mediterranean diet; no participants met criteria for low adherence category. Additionally, no significant differences in visual function or MPOD were observed between children with medium or high adherence. No correlations were observed between MPOD and any ocular parameters in either eye.
conclusionThis study found no correlation between MPOD and visual function parameters in children with medium to high adherence to the Mediterranean diet. Furthermore, adherence to the Mediterranean diet - and the associated lutein and zeaxanthin intake - showed no significant association with MPOD values or visual performance in this pediatric sample. These findings suggest that children's dietary habits may not influence MPOD values or visual function. Further studies with more diverse and larger pediatric populations, including children with low dietary adherence, are warranted to clarify these relationships.
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