Evidence map›Paper›PMID 40923934›Full record

ArticleJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2025

Bilateral Osteonecrosis of the Femoral Head and Proximal Femur After Corticosteroid Injections: A Case Report.

Annika N Hiredesai, Alejandro M Holle, Paul R Van Schuyver, David G Deckey, Nicholas E Probst, Mark J Spangehl

Abstract readCase Reports
In one paragraph

Article in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Annika N HiredesaiFrom the Mayo Clinic Alix School of Medicine, Scottsdale, AZ (Ms. Hiredesai and Mr. Holle), and the Department of Orthopedic Surgery, Mayo Clinic, Phoenix, AZ (Dr. Van Schuyver, Dr. Deckey, Dr. Probst, and Dr. Spangehl).ORCID 0009-0009-0043-1189
Alejandro M Holle
Paul R Van Schuyver
David G Deckey
Nicholas E Probst
Mark J Spangehl

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atraumatic bilateral osteonecrosis of the femoral head (ONFH) is a rare phenomenon whose etiology is not fully understood. In this report, we describe the case of a 75-year-old female patient who developed rapidly onset bilateral ONFH after intra-articular corticosteroid injections. She was treated with staged bilateral total hip arthroplasty. Several months post-operatively, she developed aseptic loosening of the left femoral implant and requiring revision of her femoral implant. The severity and distal extent of her osteonecrosis was not fully appreciated upon initial surgical management, likely increasing her risk of failure of femoral implant osseous integration. This case demonstrates that intra-articular corticosteroid injections can cause severe ONFH with extension into the proximal femur and fixation failure. Thus, the extent of osteonecrosis in the proximal femur may influence stem choice.

Indexed as

Adrenal Cortex HormonesFemurFemur Head NecrosisGlucocorticoidsAgedArthroplasty, Replacement, HipFemaleFemur HeadHumansInjections, Intra-ArticularAdrenal Cortex HormonesGlucocorticoids

Identifiers

PMID40923934
PMCPMC12419381

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.