SynthesisJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2025
Bertolotti Syndrome in the Pediatric Population: A Literature Review and Management Algorithm.
Synthesis in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- A novel C-Arm-free navigation-guided endoscopy-assisted extraforaminal decompression for L5 radiculopathy with far-out syndrome: a surgical technical note.Journal of spine surgery (Hong Kong) · 2026Article
- Septic Arthritis: A Very Uncommon but Remarkable Complication Revealing Bertolotti Syndrome in a Child.Case reports in pediatrics · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to develop a comprehensive step-wise management algorithm for Bertolotti syndrome in the pediatric population by conducting a systematic review of the current literature regarding the diagnostic evaluation, nonsurgical and surgical treatment, and outcomes.
methodsA systematic review of the literature was conducted using PubMed to identify studies focused on the management of Bertolotti syndrome in the pediatric population. Data extraction of clinical presentation, management strategies, imaging, and outcomes was completed.
resultsThirteen studies reported on 17 patients younger than 18 years with confirmed diagnosis of Bertolotti syndrome were identified. Lower back pain was the most common presenting symptom and was described in all 13 studies. Radicular pain was described in six of 13 studies. Diagnostic, intraoperative, and postoperative assessments included preoperative radiographs, CT, MRI, along with targeted injections. Treatment options ranged from nonsurgical to surgical measures. Conservative options included physical therapy, nonsteroidal anti-inflammatory medications, bracing treatment, and targeted injections. Surgical modalities included open surgical resection and posterior spinal fusion. All patients in the 13 studies demonstrated partial or complete resolution of their presenting symptoms.
conclusionsThis study provides a proposed systemic algorithm for the management of Bertolotti syndrome in the pediatric population. Based on our review of the current literature, we recommend a stepwise approach to the management of Bertolotti syndrome starting from conservative options and progressing toward surgical treatment if symptoms persist.
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