ArticleJournal of cosmetic dermatology2025
Minimally Invasive Facial Lifting Using the Versatility of Calcium Hydroxyapatite (STIIM).
Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Defining and measuring 'Lift' in soft tissue filler-based facial rejuvenation: a critical review and proposed framework.JPRAS open · 2026Article
- Review
- Minimally Invasive Facial Lifting Using the Versatility of Calcium Hydroxyapatite (STIIM).Journal of cosmetic dermatology · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionFacial aging is a multifactorial process characterized by skin laxity, volume loss, and collagen degradation. Calcium Hydroxyapatite (CaHA) is a versatile biostimulatory filler that can provide both structural support and collagen stimulation. This study evaluates a novel technique using CaHA with tailored dilutions for minimally invasive facial rejuvenation, focusing on key ligamentous structures.
objectivesTo assess the aesthetic outcomes, patient satisfaction, and safety profile of the technique using regionalized CaHA dilutions.
methodsA prospective, single-center study was conducted involving 20 subjects with facial laxity. CaHA injections were performed using three distinct dilution ratios protocols, targeting the zygomatic, temporal, and mandibular regions. Endpoints were evaluated through Face-Q questionnaires, GAIS, and standardized 2D and 3D imaging.
resultsAt 90 days, 94% of subjects reported aesthetic improvement, and the mean Face-Q Skin score increased from 43.2 ± 14.7 to 74.9 ± 14.7. These results were maintained at 360 days, with 94% of participants continuing to report improvement and a sustained FACE-Q Skin score of 77.2 ± 16.4. Investigator assessments confirmed long-term improvements, and 3D imaging showed persistent enhancement in facial contours. Adverse events were mild and self-limiting.
conclusionsThis CaHA-based technique offers a safe, minimally invasive facial lifting effect with sustained improvement over 12 months. Its effectiveness is enhanced by targeting facial ligaments and customizing dilution based on anatomical region.
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