Evidence map›Paper›PMID 40923689›Full record

Observational studyPediatric pulmonology2025

Observational Study: Lung Function and Symptom Control in Youth With Asthma up to 34 Months After COVID-19.

Kristina Gaietto, Nicholas Bergum, Daniel J Weiner, Erick Forno

Abstract readObservational Study
In one paragraph

Observational study in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Asthma control and exacerbation risk following SARS-CoV-2 infection in the post-acute COVID-19 phase: a systematic review.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2026
    Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kristina GaiettoDepartment of Pediatrics, Division of Pulmonology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-4618-2984
Nicholas BergumUniversity of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Daniel J WeinerDepartment of Pediatrics, Division of Pulmonology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-8245-1961
Erick FornoDepartment of Pediatrics, Division of Pulmonology, Indiana University of School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0001-6497-9885

Funding

Molecular Basis of Pediatric DiseaseK12HD052892 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TERENCE S. DERMODY · 2007 to 2026
$6.5M
Obesity and Childhood Asthma: The Role of Adipose TissueR01HL149693 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FORNO, ERICK · 2020 to 2024
$3.0M
Advancing telemedicine in pulmonology: acoustic-waveform respiratory evaluation (AWARE) via sensing and machine learning on smartphonesR01HL170368 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI Erick Forno, Wei Gao · 2024 to 2026
$1.9M
Dr. Gaietto is supported by K12 Grant HD052892 from the US National Institutes of Health (NIH) and the Children's Hospital of Pittsburgh Scholars Grant. Dr Forno's effort is partly supported by grants HL149693 and HL170368 from the US NIH.NHLBI NIH HHS R01 HL149693NHLBI NIH HHS R01 HL170368NICHD NIH HHS K12 HD052892
6 · The paper itself

Abstract

introductionPrior studies of pediatric asthma control and lung function after COVID-19 have been limited by short follow-up intervals. We aimed to evaluate symptom control and lung function in children with asthma up to 34 months post-COVID-19.

methodsWe conducted a prospective observational chart review study. We reviewed electronic health records of children with asthma in the Western Pennsylvania COVID-19 Registry, abstracting pre- and all post-infection spirometry results and Childhood Asthma Control Test (C-ACT) or Asthma Control Test (ACT) scores (to measure symptom control) through August 2023. We conducted adjusted mixed models with linear spline to compare C-ACT/ACT or FEV

resultsWe found no significant differences between baseline and post-infection symptom control (n = 267) or lung function (n = 196). Of the 28% of children who had worse lung function at initial follow-up, 34% fully recovered at final follow-up. Of the 19% with worse C-ACT/ACT score at initial follow-up, 38% fully recovered at final follow-up. Final follow-up median C-ACT/ACT scores and mean FEV

conclusionThere were no significant differences between baseline and follow-up symptom control or lung function in children with asthma up to 34 months post-COVID-19. Only a small proportion of children worsened and did not recover, and decrements were generally small. Obesity was associated with impaired symptom control recovery.

Indexed as

AsthmaCOVID-19LungAdolescentChildFemaleFollow-Up StudiesHumansMaleProspective StudiesRespiratory Function TestsSARS-CoV-2SpirometrychildpediatricsSARS‐CoV‐2

Identifiers

PMID40923689
PMCPMC12418911

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.