SynthesisTropical medicine & international health : TM & IH2025
Mapping the Burden of Tegumentary Leishmaniasis in South America: A Systematic Review and Meta-Analysis.
Synthesis in Tropical medicine & international health : TM & IH, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mapping the Burden of Tegumentary Leishmaniasis in South America: A Systematic Review and Meta-Analysis.Tropical medicine & international health : TM & IH · 2025Pooled it
- Evaluation of a commercial real-time PCR assay targeting Leishmania spp. with microscopically positive skin biopsies obtained from Nigerian patients.European journal of microbiology & immunology · 2026Article
- BrazilianToxins · 2026Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIn recent years, the global burden of tegumentary leishmaniasis (TL) has significantly increased in the Americas.
objectiveTo estimate the prevalence of TL in South America based on publications from the past 13 years.
methodsThree databases were searched, and articles were selected based on inclusion criteria and methodological relevance. The random effects model was used to calculate pooled prevalence, and heterogeneity was assessed with the I
resultsOut of the 225 articles initially identified, six studies remained eligible for review and meta-analysis. No publication bias was found. TL prevalence in South America ranged from 0.2% to 87.7%, showing significant heterogeneity (I
conclusionsTL prevalence varied widely across countries, reflecting national epidemiological disparities. High positivity rates in suspicious samples and molecular detection in samples confirmed by microscopy underscore the importance of accurate diagnosis and clinical expertise. This meta-analysis emphasises the need for tailored health policies and accessible laboratory diagnoses to guide disease control strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.