Evidence map›Paper›PMID 40923411›Full record

ArticleJournal of the American Chemical Society2025

Harnessing Dynamic Heteroleptic Complexation for Self-Assembly of Robust Nested Metallo-Supramolecular Cages.

Soumyakanta Prusty, Hung-Kai Hsu, Mahesh Madasu, Alisha Rani, Jun-Hao Fu, Lin-Ting Lin, Ming-Hao Lee, Ming-Wen Chu, Chun-Hong Kuo, Yi-Tsu Chan

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In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Soumyakanta PrustyDepartment of Chemistry, National Taiwan University, Taipei 106319, Taiwan.
Hung-Kai HsuDepartment of Chemistry, National Taiwan University, Taipei 106319, Taiwan.ORCID 0000-0001-9347-2290
Mahesh MadasuDepartment of Chemistry, National Taiwan University, Taipei 106319, Taiwan.ORCID 0000-0002-0822-2244
Alisha RaniDepartment of Chemistry, National Taiwan University, Taipei 106319, Taiwan.
Jun-Hao FuDepartment of Chemistry, National Taiwan University, Taipei 106319, Taiwan.
Lin-Ting LinDepartment of Chemistry, National Taiwan University, Taipei 106319, Taiwan.
Ming-Hao LeeCenter for Condensed Matter Sciences and Center of Atomic Initiative for New Materials, National Taiwan University, Taipei 106319, Taiwan.
Ming-Wen ChuCenter for Condensed Matter Sciences and Center of Atomic Initiative for New Materials, National Taiwan University, Taipei 106319, Taiwan.
Chun-Hong KuoDepartment of Applied Chemistry, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.ORCID 0000-0001-6633-8985
Yi-Tsu ChanDepartment of Chemistry, National Taiwan University, Taipei 106319, Taiwan.ORCID 0000-0001-9658-2188

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The exclusive formation of artificial multicomponent assemblies remains a significant challenge, in contrast to the well-established organization observed in natural systems, due to intrinsic entropic constraints. To overcome this limitation, recent efforts have been focused on developing precision self-assembly strategies for the rational construction of such architectures. Here, we construct an ideal complementary pair of 2,2':6',2″-terpyridine (tpy)-based ligands by fine-tuning the substituent bulkiness, which enables the quantitative formation of robust nested cages through efficient dynamic heteroleptic complexation with multivalent coordination. The multivalent ligand design proves essential for successful self-assembly, as the smaller incarcerated cage cannot be independently synthesized in an exclusive manner. Notably, the improved solubility and exceptional stability of the nested cage even at low concentrations allow for structural characterization by high-field nuclear magnetic resonance (NMR) spectroscopy, solution-based small-angle X-ray scattering (SAXS), and scanning transmission electron microscopy (STEM). Moreover, its well-defined internal cavity permits the in situ reductive formation of gold nanoparticles, demonstrating its potential as a functional nanoreactor.

Identifiers

PMID40923411
PMCPMC12447513

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.