Evidence map›Paper›PMID 40923401›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Super-Resolution Compatible DNA Labeling Technique Reveals Chromatin Mobility and Organization Changes During Differentiation.

Maruthi K Pabba, Miroslav Kuba, Tomáš Kraus, Kerem Celikay, Janis Meyer, Sunil Kumar Pradhan, Andreas Maiser, Hartmann Harz, Heinrich Leonhardt, Karl Rohr and 2 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Maruthi K PabbaCell Biology and Epigenetics, Department of Biology, Technical University of Darmstadt, 64287, Darmstadt, Germany.ORCID https://orcid.org/0000-0003-2855-1392
Miroslav KubaInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague 6, CZ-16000, Czech Republic.
Tomáš KrausInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague 6, CZ-16000, Czech Republic.ORCID https://orcid.org/0000-0002-0055-5853
Kerem CelikayBiomedical Computer Vision Group, BioQuant, IPMB, Heidelberg University, Baden-Würtenberg, 69120, Heidelberg, Germany.
Janis MeyerBiomedical Computer Vision Group, BioQuant, IPMB, Heidelberg University, Baden-Würtenberg, 69120, Heidelberg, Germany.
Sunil Kumar PradhanCell Biology and Epigenetics, Department of Biology, Technical University of Darmstadt, 64287, Darmstadt, Germany.
Andreas MaiserHuman Biology and Bioimaging, Faculty of Biology, Ludwig Maximilians University Munich, 81377, Munich, Germany.ORCID https://orcid.org/0000-0002-2349-5822
Hartmann HarzHuman Biology and Bioimaging, Faculty of Biology, Ludwig Maximilians University Munich, 81377, Munich, Germany.ORCID https://orcid.org/0000-0003-1218-2107
Heinrich LeonhardtHuman Biology and Bioimaging, Faculty of Biology, Ludwig Maximilians University Munich, 81377, Munich, Germany.ORCID https://orcid.org/0000-0002-5086-6449
Karl RohrBiomedical Computer Vision Group, BioQuant, IPMB, Heidelberg University, Baden-Würtenberg, 69120, Heidelberg, Germany.
Michal HocekInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague 6, CZ-16000, Czech Republic.ORCID https://orcid.org/0000-0002-1113-2047
M Cristina CardosoCell Biology and Epigenetics, Department of Biology, Technical University of Darmstadt, 64287, Darmstadt, Germany.ORCID https://orcid.org/0000-0001-8427-8859

Funding

Bundesministerium für Bildung und Forschung Project-ID 031A537CDeutsche Forschungsgemeinschaft 240245660Deutsche Forschungsgemeinschaft 529989072Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) 213249687Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) 393547839Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) 422857584Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) 529989072Grantová Agentura České Republiky project 20-00885X
6 · The paper itself

Abstract

Chromatin dynamics play a crucial role in cellular differentiation, yet tools for studying global chromatin mobility in living cells remain limited. Here, a novel probe is developeded for the metabolic labeling of chromatin and tracking its mobility during neural differentiation. The labeling system utilizes a newly developed silicon rhodamine-conjugated deoxycytidine triphosphate (dC

Indexed as

Cell DifferentiationChromatinDNAInduced Pluripotent Stem CellsNeural Stem CellsHumansNeuronsStaining and LabelingChromatinDNAchromatin mobilitydCSiRTPhuman iPSC differentiationSNTT1STED

Identifiers

PMID40923401
PMCPMC12677680

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.