Evidence map›Paper›PMID 40923336›Full record

Trial reportKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2026

Medial parapatellar surgical approach leads to greater loss of postural sway complexity compared to mid-vastus approach in women undergoing total knee arthroplasty.

Vasileios Mylonas, Stylianos Grigoriadis, Dimitris Metaxiotis, Eleftherios Kellis, Nick Stergiou, Thomas Nikodelis

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vasileios MylonasDivision of Biomechanics and Research Development, Department of Biomechanics and Center for Research in Human Movement Variability, University of Nebraska at Omaha, Omaha, Nebraska, USA.ORCID https://orcid.org/0000-0001-8820-2800
Stylianos GrigoriadisBiomechanics Laboratory, School of Physical Education & Sport Science at Thessaloniki, Aristotle University of Thessaloniki, Thessaloniki, Greece.ORCID https://orcid.org/0000-0003-2868-4419
Dimitris Metaxiotis2nd Orthopaedic Department, General Hospital of Thessaloniki "Papageorgiou", Thessaloniki, Greece.
Eleftherios KellisLaboratory of Neuromechanics, School of Physical Education & Sport Science at Serres, Aristotle University of Thessaloniki, Serres, Greece.ORCID https://orcid.org/0000-0002-8179-6340
Nick StergiouDivision of Biomechanics and Research Development, Department of Biomechanics and Center for Research in Human Movement Variability, University of Nebraska at Omaha, Omaha, Nebraska, USA.ORCID https://orcid.org/0000-0002-9737-9939
Thomas NikodelisBiomechanics Laboratory, School of Physical Education & Sport Science at Thessaloniki, Aristotle University of Thessaloniki, Thessaloniki, Greece.ORCID https://orcid.org/0000-0002-5305-1472

Funding

Visual control of locomotion in people with Parkinsons diseaseP20GM109090 · NIGMS · UNIVERSITY OF NEBRASKA OMAHA · PI STERGIOU, NIKOLAOS · 2014 to 2023
$20.5M
Tissue Analysis Core (TAC)P20GM152301 · NIGMS · UNIVERSITY OF NEBRASKA OMAHA · PI Yury Salkovskiy · 2024 to 2026
$8.8M
NIH HHS P20GM109090NIH HHS P20GM152301
6 · The paper itself

Abstract

purposeTotal knee arthroplasty (TKA) is associated with acute postoperative effects that increase the risk of falls. These effects differ between the medial parapatellar (PP) and mid-vastus (MV) surgical techniques but have not been evaluated in terms of postural sway complexity. Loss of this complexity leads to increased randomness in the center of pressure and higher fall risk. This exploratory comparative analysis addresses this knowledge gap by examining how PP and MV techniques affect postural sway complexity in women.

methodsTwenty women with osteoarthritis (OA) were randomly assigned to TKA via the PP or MV approach. Postural sway data were collected at: 1 day before the surgery (Pre), 5 days (Post), 2 weeks, and 1 month post-surgery. We also included an age- and sex-matched healthy control group (n = 11) with a single assessment of their postural sway. The temporal structure of variability was evaluated in terms of its complexity. We quantified the complexity of postural sway using detrended fluctuation analysis (DFA) and multi-scale entropy (MSE).

resultsThe α exponent (DFA) and MSE values showed significant effects of time in both axes, with both surgical groups exhibiting a shift towards more random patterns following TKA. When compared to controls, the PP group exhibited a significantly lower α exponent, indicative of more random patterns, at 2 weeks and 1 month but not at Pre and Post, while no such differences were observed for the MV group. Lower α exponent and higher MSE values reflect reduced sway complexity.

conclusionsThese findings suggest that TKA leads to loss of complexity in women during the postoperative stage, with the PP approach resulting in more pronounced reductions relative to healthy controls than the MV approach. Future studies should explore the long-term effects of TKA on postural sway complexity and the impact of rehabilitation protocols. LEVEL OF EVIDENCE: N/A.

Indexed as

Arthroplasty, Replacement, KneeOsteoarthritis, KneePatellaPostural BalanceQuadriceps MuscleAccidental FallsAgedCase-Control StudiesFemaleHumansMiddle AgedPostoperative Complicationsbalancecomplexityosteoarthritisposturevariability

Identifiers

PMID40923336
PMCPMC13122746

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.