Evidence map›Paper›PMID 40923048›Full record

ReviewTherapeutic advances in medical oncology2025

Pregnancy and breast cancer in young women: current updates and future directions.

Shiliang Zhang, Sena B Guclu, Marla Lipsyc-Sharf, Nimmi S Kapoor

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Therapeutic advances in medical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shiliang ZhangDivision of Hematology and Oncology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.ORCID https://orcid.org/0009-0003-1600-2166
Sena B GucluSchool of Medicine, Koç University, Istanbul, Turkey.
Marla Lipsyc-SharfDivision of Hematology and Oncology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-4071-6383
Nimmi S KapoorDivision of Surgical Oncology, Department of Surgery, University of California, Los Angeles, 15503 Ventura Blvd, Suite 150, Los Angeles, CA 90095, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relationship between pregnancy and breast cancer is complicated. On one hand, pregnancy can influence breast cancer risk and tumor biology, and on the other, a breast cancer diagnosis and its subsequent management can significantly affect fertility, family planning, and future pregnancies. This interaction presents challenges unique to young women with breast cancer (YWBC). This review provides an updated overview of YWBC and pregnancy-associated breast cancer (PABC), including the rising prevalence of YWBC, current understanding of the biology of PABC and its subtypes, and the management of PABC. We address the critical issue of how breast cancer treatment impacts family planning and future pregnancies, including current data on interrupting endocrine treatment for pregnancy. Additionally, we examine recent advancements in early-stage breast cancer as well as gaps in knowledge regarding how targeted treatments affect ovarian reserve. Finally, we highlight key areas of future research that could improve the prevention, management, and understanding of cancer treatment's impact on fertility in YWBC.

Indexed as

breast cancerchemotherapyhormone therapypostpartumpregnancytargeted therapy

Identifiers

PMID40923048
PMCPMC12414122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.