Evidence map›Paper›PMID 40923030›Full record

ArticleCancer pathogenesis and therapy2025

Economic burden and health-related quality of life in Chinese patients with mycosis fungoides and Sézary syndrome.

Yuankai Shi, Jianfang Sun, Huiping Sun, Mingzhi Zhang, Zhiming Li, Haifeng Zhao, Linna Xie, Wenrong Huang, Xiaojing Yan

Abstract read
In one paragraph

Article in Cancer pathogenesis and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuankai ShiDepartment of Medical Oncology, Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China.
Jianfang SunDepartment of Dermatology, Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, Jiangsu 210042, China.
Huiping SunDepartment of Hematology, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200025, China.
Mingzhi ZhangDepartment of Medical Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.
Zhiming LiDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, China.
Haifeng ZhaoDepartment of Hematology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin 300060, China.
Linna XieDepartment of Lymphoma, Shandong Cancer Hospital and Institute, Jinan, Shandong 250117, China.
Wenrong HuangDepartment of Lymphoma, Chinese PLA General Hospital, Beijing 100853, China.
Xiaojing YanDepartment of Hematology, The First Hospital of China Medical University, Shenyang, Liaoning 110001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The health-related quality of life (HRQoL), economic burden, and diagnostic and treatment status of Chinese patients with mycosis fungoides (MF) and Sézary syndrome (SS) remain largely unknown. This study assessed patient characteristics, HRQoL, and economic burden among Chinese patients with MF and SS through a cross-sectional survey. Methods: Eligible patients were aged ≥18 years with a pathologically confirmed diagnosis of MF or SS and were either currently receiving or had received disease-specific treatment within the past year. Patients completed a paper-based quantitative survey covering four components: patient demographics, diagnosis and treatment journey, economic burden, and HRQoL instrument. Results: Between July 21, 2022, and October 24, 2022, 61 eligible patients participated in this study, of whom 91.8% (56/61) had MF and 8.2% (5/61) had SS. The total cost for patients with MF and SS was Chinese Yuan (CNY) 86,729 (US Dollar [USD] 12,425). The total cost for patients with early-stage disease was significantly lower than that for patients with advanced-stage disease (CNY 43,379 Conclusions: Chinese patients with MF or SS, especially advanced-stage patients, experience high economic burden and compromised HRQoL, which underscore the need for improved access to affordable treatments and supportive care measures to reduce the financial burden and enhance the well-being of these patients. Healthcare policies and interventions should prioritize early diagnosis and effective management to improve the treatment outcome and reduce its associated costs.

Indexed as

Health-related quality of lifeMycosis fungoidesPatient-reported outcomesSézary syndrome

Identifiers

PMID40923030
PMCPMC12414272

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.