Evidence map›Paper›PMID 40923006›Full record

ArticleDrug design, development and therapy2025

Anticancer, Antioxidant and Antimicrobial Activity of

Serap Doğan, Ahmet Meşe, Mehmet Fırat Baran, Ayse Baran, Necmettin Aktepe, Elham Ahmadian, Ali Jimale Mohamed, Aziz Eftekhari, Hüsnü Aktaş

Abstract read
In one paragraph

Article in Drug design, development and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Protective effect ofOpen veterinary journal · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Serap DoğanMardin Artuklu University, Kızıltepe Faculty of Agricultural Sciences and Technologies, Department of Field Crops, Mardin, Artuklu, 47200, Türkiye.ORCID 0000-0002-1099-6919
Ahmet MeşeDepartment of Chemistry, Graduate Education Institute, Mardin Artuklu University, Mardin, 47200, Turkey.ORCID 0009-0009-5884-1746
Mehmet Fırat BaranDepartment of Food Technology, Vocational School of Technical Sciences, Batman University, Batman, 72000, Turkey.ORCID 0000-0001-8133-6670
Ayse BaranMardin Artuklu University, Kızıltepe Faculty of Agricultural Sciences and Technologies, Department of Field Crops, Mardin, Artuklu, 47200, Türkiye.ORCID 0000-0002-2317-0489
Necmettin AktepeMardin Artuklu University, Faculty of Health Sciences, Department of Nursing, Mardin, 47200, Türkiye.ORCID 0000-0003-2192-9049
Elham AhmadianKidney Research Center, Tabriz University of Medical Sciences, Tabriz, 51666-15731, Iran.ORCID 0000-0002-3773-5866
Ali Jimale MohamedDepartment of Pharmacology, Faculty of Medicine, Somali National University, Mogadishu, 801, Somalia.ORCID 0009-0001-5567-6230
Aziz EftekhariDepartment of Biochemistry, Faculty of Science, Ege University, Izmir, 35040, Turkey.ORCID 0000-0003-0274-4479
Hüsnü AktaşMardin Artuklu University, Kızıltepe Faculty of Agricultural Sciences and Technologies, Department of Field Crops, Mardin, Artuklu, 47200, Türkiye.ORCID 0000-0001-6943-2109

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study was conducted to determine and compare the antioxidant, cytotoxic, and antimicrobial effects of spindle leaves of Methods: Total phenolic content was measured using the Folin-Ciocalteu method, phenolic compound analysis by liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) and antimicrobial effect by the minimum inhibition concentration (MIC) method. The free radical scavenging activity was determined by t Results: High amounts of gallic acid, protocatechuic acid, and o-coumaric acid were identified as phenolic compounds. Conclusion: Our study will contribute greatly to the search for anticancer and antimicrobial agents, especially from a pharmacological perspective, by examining biological activity using three different methods.

Indexed as

Anti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsAntineoplastic Agents, PhytogenicAntioxidantsElaeagnaceaePlant ExtractsPlant LeavesBiphenyl CompoundsCandida albicansCell Line, TumorCell ProliferationCell SurvivalDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansAnti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsAntineoplastic Agents, PhytogenicAntioxidantsBiphenyl CompoundsPlant Extractsantimicrobial activitycytotoxicityE. angustifolia antioxidantphenolics

Identifiers

PMID40923006
PMCPMC12414469

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.