Evidence map›Paper›PMID 40922914›Full record

ArticleAnnals of gastroenterological surgery2025

Survival Outcomes of Esophageal Squamous Cell Carcinoma Patients Who Underwent Salvage Esophagectomy: A Literature Review and Results From Two High-Volume Centers.

Kotaro Sugawara, Koichi Yagi, Takashi Fukuda, Shoh Yajima, Daiji Oka, Yoshiyuki Miwa, Shuichiro Oya, Asami Okamoto, Raito Asaoka, Yoshifumi Baba

Abstract read
In one paragraph

Article in Annals of gastroenterological surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kotaro SugawaraDepartment of Gastrointestinal Surgery, Graduate School of Medicine The University of Tokyo Tokyo Japan.ORCID https://orcid.org/0000-0002-3272-1748
Koichi YagiDepartment of Gastrointestinal Surgery, Graduate School of Medicine The University of Tokyo Tokyo Japan.
Takashi FukudaDepartment of Gastroenterological Surgery Saitama Cancer Center Hospital Saitama Japan.
Shoh YajimaDepartment of Gastrointestinal Surgery, Graduate School of Medicine The University of Tokyo Tokyo Japan.
Daiji OkaDepartment of Gastroenterological Surgery Saitama Cancer Center Hospital Saitama Japan.
Yoshiyuki MiwaDepartment of Gastrointestinal Surgery, Graduate School of Medicine The University of Tokyo Tokyo Japan.
Shuichiro OyaDepartment of Gastrointestinal Surgery, Graduate School of Medicine The University of Tokyo Tokyo Japan.
Asami OkamotoDepartment of Gastrointestinal Surgery, Graduate School of Medicine The University of Tokyo Tokyo Japan.
Raito AsaokaDepartment of Gastrointestinal Surgery, Graduate School of Medicine The University of Tokyo Tokyo Japan.
Yoshifumi BabaDepartment of Gastrointestinal Surgery, Graduate School of Medicine The University of Tokyo Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to investigate survival outcomes, the efficacy of lymph node (LN) dissection, and recurrence patterns in patients who underwent salvage surgery (SALV) for esophageal squamous cell carcinoma (ESCC) after definitive chemoradiotherapy (dCRT). Methods: We retrospectively reviewed 69 patients with clinical stage I-IV thoracic ESCC who underwent SALV. Recurrence patterns and the distribution of LN metastases were analyzed according to the primary tumor location. Results: The 90-day mortality rate was 2.9%, and the 3-year overall survival (OS) rate of the 69 patients was 47.1%. OS curves were significantly stratified by the presence of abdominal LN metastases ( Conclusions: Abdominal LN metastases had a negative impact on survival in ESCC patients who underwent SALV. Clinically positive LNs should be dissected, provided it is technically feasible. The tumor location might influence the distribution and prognostic impact of pathological LN metastases.

Indexed as

definitive chemoradiotherapyesophageal squamous cell carcinomalocoregional recurrencelymph node dissectionsalvage esophagectomy

Identifiers

PMID40922914
PMCPMC12414584

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.