Evidence map›Paper›PMID 40922876›Full record

ArticleCureus2025

Recurrent Malignant Struma Ovarii With Peritoneal Implants Following Prior Thyroid Carcinoma Treatment.

Fiorella Apuy Rodríguez, María Luisa Alvarado Mora, María Laura Alvarado Fernández, María Jesús Arias Alvarado

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fiorella Apuy RodríguezFaculty of Medicine, University of Costa Rica, San José, CRI.
María Luisa Alvarado MoraFaculty of Medicine, University of Costa Rica, San José, CRI.
María Laura Alvarado FernándezFaculty of Medicine, University of Costa Rica, San José, CRI.
María Jesús Arias AlvaradoFaculty of Medicine, University of Costa Rica, San José, CRI.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Struma ovarii (SO) is a rare form of ovarian teratoma predominantly composed of thyroid tissue. While most cases follow a benign course, some may exhibit malignant transformation or extra-ovarian spread. We present the case of a 43-year-old woman with a history of SO previously treated with right oophorectomy and systemic chemotherapy, along with a separate diagnosis of papillary thyroid carcinoma managed with total thyroidectomy and radioactive iodine ablation. She remained asymptomatic for several years until routine surveillance imaging revealed stable pelvic lesions. Surgical exploration via exploratory laparotomy and suboptimal cytoreduction was performed, leading to the resection of multiple peritoneal implants. Histopathology confirmed recurrence of malignant SO. Postoperative recovery was uneventful, and systemic therapy was deferred due to limited supporting evidence. This case highlights the importance of clinical suspicion, surveillance, and individualized surgical management for recurrent SO.

Indexed as

malignant struma ovariipapillary thyroid carcinomaperitoneal implantsrecurrent ovarian neoplasmstruma ovarii

Identifiers

PMID40922876
PMCPMC12414295

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.