Evidence map›Paper›PMID 40922859›Full record

ArticleCureus2025

Streptococcal Toxic Shock Syndrome: A Case Report Highlighting the Importance of Early Recognition and Intervention.

Molly E Boyko

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Molly E BoykoInternal Medicine, St Luke's Hospital, Easton, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Streptococcal toxic shock syndrome (STSS) is a rare but life-threatening illness characterized by rapid progression to multi-organ failure. This is a case of a middle-aged male patient who initially presented with localized chest wall pain, erythema, vomiting, and diarrhea. These nonspecific symptoms rapidly progressed to systemic shock and multi-organ dysfunction, including acute kidney injury, pleural effusions, demand ischemia of the heart, and the development of a characteristic diffuse, sunburn-like rash. The likely inciting factor was a soft-tissue infection of the chest wall. The patient was treated with broad-spectrum intravenous antibiotics and supportive care in the intensive care unit and step-down unit. Following stabilization after the acute phase, the patient was readmitted due to complications and faced a prolonged recovery. Early symptoms are often vague, and many cases are initially misdiagnosed, highlighting the importance of early diagnostic consideration. This case demonstrates the impact of prompt recognition and timely intervention in STSS. Additionally, it emphasizes the importance of ongoing follow-up due to the risk of long-term sequelae. Clinicians should maintain a high index of suspicion when evaluating patients with rapidly progressing soft-tissue infections and systemic signs.

Indexed as

case reportcellulitisseverity of cellulitissoft-tissue infectionstreptococcal bacteremiastreptococcal toxic shock syndromestss treatment

Identifiers

PMID40922859
PMCPMC12414524

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.