ArticleCureus2025
A Shocking Spiral: Methamphetamine-Induced Electrical Storm in End-Stage Cardiomyopathy.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An electrical storm (ES) represents one of cardiology's most formidable and life-threatening crises, marked by relentless ventricular arrhythmias within a 24-hour period. While stimulant cardiotoxicity is an escalating concern, the devastating role of methamphetamine in triggering refractory ES and its deleterious outcomes in advanced cardiomyopathy, particularly within the critical care setting, remains profoundly underreported and poorly understood. We present the urgent case of a 44-year-old male with end-stage dilated cardiomyopathy and chronic, heavy methamphetamine abuse, who spiraled into incessant ventricular tachycardia (VT) storm following acute methamphetamine use. Despite aggressive anti-arrhythmic therapy including over 35 defibrillation shocks, he developed profound cardiogenic shock, intractable arrhythmias, and a rapid progression to multi-organ failure. Maximal support with both extracorporeal membrane oxygenation (ECMO) and intra-aortic balloon pump (IABP) was required, alongside continuous renal replacement therapy (CRRT) for escalating hyperkalemia and renal failure. Despite heroic multidisciplinary efforts, his course was complicated by recurring sepsis and ultimately culminated in progressive multi-organ dysfunction, leading to withdrawal of care on hospital day 16. This critical case study illuminates the therapeutic challenges posed by methamphetamine-induced VT storm in advanced cardiomyopathy. It vividly underscores the imperative for immediate recognition, rapid initiation of a multidisciplinary approach, and aggressive supportive care for such catastrophic arrhythmogenic crises. Furthermore, it highlights the devastating, often irreversible synergy between stimulant cardiotoxicity and structural heart disease, demanding urgent awareness among clinicians to mitigate this growing public health emergency.
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