Evidence map›Paper›PMID 40922794›Full record

ArticleJAACAP open2025

Examining Alternative Treatment Settings for Adolescents With Suicidal Thoughts During the COVID-19 Pandemic.

Jennifer Combs, Ping-I Lin, Melissa P DelBello, Adam C Carle, Jeffrey A Bridge, David A Axelson, Victor Fornari, Vera Feuer, Graham J Emslie, Betsy D Kennard and 3 more

Registry-linked trialAbstract read
In one paragraph

Article in JAACAP open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04625686 (A Multi-Site, Non-Interventional Study to Compare the Outcomes of Psychiatric Treatment of Suicidal Adolescents in Different Treatment Settings), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04625686 completednot on this map

A Multi-Site, Non-Interventional Study to Compare the Outcomes of Psychiatric Treatment of Suicidal Adolescents in Different Treatment Settings

TypeobservationalSponsorChildren's Hospital Medical Center, CincinnatiRan2020 to 2021Enrolled249ConditionsSuicidal IdeationArmsMental Health Treatment
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jennifer CombsCincinnati Children's Hospital, Cincinnati, Ohio.
Ping-I LinSaint Louis University School of Medicine, St. Louis Missouri, and the University of New South Wales, Australia.
Melissa P DelBelloUniversity of Cincinnati College of Medicine, Cincinnati, Ohio.
Adam C CarleCincinnati Children's Hospital, Cincinnati, Ohio.
Jeffrey A BridgeNationwide Children's Hospital, Columbus, Ohio.
David A AxelsonNationwide Children's Hospital, Columbus, Ohio.
Victor FornariNorthwell Health and Cohen Children's Medical Center, New Hyde Park, New York.
Vera FeuerNorthwell Health and Cohen Children's Medical Center, New Hyde Park, New York.
Graham J EmslieUT Southwestern Medical Center, Dallas, Texas.
Betsy D KennardUT Southwestern Medical Center, Dallas, Texas.
Stephen C PorterCincinnati Children's Hospital, Cincinnati, Ohio.
Michael T SorterCincinnati Children's Hospital, Cincinnati, Ohio.
Drew BarzmanCincinnati Children's Hospital, Cincinnati, Ohio.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Suicide is a leading cause of death for adolescents in the United States. Alternative settings to treat suicidal ideation (SI) are needed. Study primary objectives include evaluating the safety and effectiveness of telehealth crisis intervention services (CIS) and in-person outpatient crisis intervention clinics (OCIC) relative to the current standard of care of inpatient psychiatric hospitalization. A secondary aim seeks to assess changes in suicidal ideation, and patient and parent treatment satisfaction. Method: The study team, consisting of study staff at 4 sites, conducted an observational longitudinal study of patients (12-18 years of age) who were seen in the Emergency Department (ED) for suicidality and were referred to inpatient treatment, in-person OCIC, or telehealth CIS. Primary outcome data, including recurrent ED visits and hospitalizations because of SI, suicide attempts, and life satisfaction, were collected for 24 weeks. All analyses were adjusted for age, sex, and baseline suicidality severity scores. A total of 249 patients were enrolled. Results: There were no statistically significant differences in suicide attempts, time to first suicide attempt, ED visits, hospitalizations, and life satisfaction among the 3 treatment arms. There was no statistically significant difference in outcomes for treatment satisfaction among the treatment groups. Conclusion: In this observational study, in-person OCIC and telehealth CIS did not have significantly different outcomes from the current standard of care of inpatient psychiatric hospitalization. This broadens the scope of services that appear to be safe and effective for adolescents experiencing moderate suicidal thoughts. Future research using randomized controlled trials to clarify the causal effect of different interventions is warranted. Clinical trial registration information: Observational Study to Compare Outcomes of Different Psychiatric Treatment of Suicidal Adolescents (Pre-START); https://clinicaltrials.gov/study/NCT04625686. Diversity Inclusion Statement: We worked to ensure that the study questionnaires were prepared in an inclusive way. The author list of this paper includes contributors from the location and/or community where the research was conducted who participated in the data collection, design, analysis, and/or interpretation of the work.

Indexed as

adolescentsuicidetreatment

Identifiers

PMID40922794
PMCPMC12414334

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.