Evidence map›Paper›PMID 40922792›Full record

ArticleJAACAP open2025

Relationships Between Adolescent Perception of Family Functioning and Affective Symptomatology.

Tram N B Nguyen, Aaron B Chance, Chloe Roske, Emily Chase, Tamar B Rubinstein, Amanda Zayde, Wenzhu B Mowrey, Vilma Gabbay

Abstract read
In one paragraph

Article in JAACAP open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Equivalence of psychiatric structured interviews and symptom checklists in predicting health-related quality of life in children with chronic physical illness.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tram N B NguyenAlbert Einstein College of Medicine, Bronx, New York.
Aaron B ChanceAlbert Einstein College of Medicine, Bronx, New York.
Chloe RoskeHarvard University, Cambridge, Massachusetts.
Emily ChaseOhio State University, Columbus, Ohio.
Tamar B RubinsteinAlbert Einstein College of Medicine, Bronx, New York.
Amanda ZaydeAlbert Einstein College of Medicine, Bronx, New York.
Wenzhu B MowreyAlbert Einstein College of Medicine, Bronx, New York.
Vilma GabbayNathan S. Kline Institute for Psychiatric Research, Orangeburg, New York.

Funding

Engagement and Depression in Adolescents and Young Adults with Childhood-onset LupusK23AR080803 · NIAMS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Tamar B Rubinstein · 2023 to 2026
$696k
NIAMS NIH HHS K23 AR080803
6 · The paper itself

Abstract

Objective: The bidirectional relationships between family functioning and adolescent depressive and anxiety disorders have been documented. However, categorical diagnostic criteria for these disorders often mask the high variability of symptom severity across individuals sharing the same diagnoses. Accounting for such heterogeneity, this study examined the associations between domains of family functioning and depression, anxiety, and anhedonia symptoms from the adolescent perspective using a dimensional approach. Method: Semistructured diagnostic interviews and self-reported measures for depression, anxiety, and anticipatory and consummatory anhedonia were used to evaluate adolescents. Participants' perception of 7 aspects of family life was assessed with the Family Assessment Device. Bivariate assessments of associations between family subscales and symptom severity scores were conducted. Subsequently, regression models were employed to investigate these relationships while adjusting for age, sex, race, ethnicity, and multiple comparisons. Results: Data from 79 adolescents (15.0 ± 1.84 years old; 61.8% biologically female) were analyzed, including 59 participants with psychopathology and 19 control participants. Adolescents with psychiatric symptoms perceived lower levels of family Problem Solving, Communication, and General Functioning relative to control participants. Depression severity was associated with Problem Solving, Communication, Roles, Affective Responsiveness, and General Functioning. Anxiety was associated with Problem Solving, Roles, and General Functioning. These relationships remained significant following adjustments for covariates and multiple comparisons correction. Anhedonia subconstructs and perceived family functioning associations were not as robust, suggesting a different etiological pathway. Conclusion: These findings support the intertwined relationships between adolescent mood and anxiety processes and perceived family functioning factors. Future studies should examine larger samples and incorporate parents' perspectives. Diversity & Inclusion Statement: We worked to ensure sex and gender balance in the recruitment of human participants. We worked to ensure that the study questionnaires were prepared in an inclusive way. We worked to ensure race, ethnic, and/or other types of diversity in the recruitment of human participants. One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented sexual and/or gender groups in science. We actively worked to promote sex and gender balance in our author group. We actively worked to promote inclusion of historically underrepresented racial and/or ethnic groups in science in our author group. While citing references scientifically relevant for this work, we also actively worked to promote sex and gender balance in our reference list. While citing references scientifically relevant for this work, we also actively worked to promote inclusion of historically underrepresented racial and/or ethnic groups in science in our reference list. The author list of this paper includes contributors from the location and/or community where the research was conducted who participated in the data collection, design, analysis, and/or interpretation of the work.

Indexed as

adolescenceanhedoniaanxietydepressionfamily functioning

Identifiers

PMID40922792
PMCPMC12414323

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.