ArticleJAACAP open2025
Autism Spectrum Disorder and Grandmother's Race, Ethnicity, and Nativity.
Article in JAACAP open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study investigated associations between offspring autism spectrum disorder (ASD) and grandmother's race, ethnicity, and nativity. Method: This is a statewide multigenerational California birth cohort linkage study using birth records from the California Department of Public Health and diagnostic records from the California Department of Developmental Services with primary diagnosis of autistic disorder and codes for intellectual disabilities (ID). The analytical study population includes 1,743,177 mother-child pairs of children born between 2001 and 2019 to mothers who were born between 1983 and 2001. Grandmother's self-reported race, ethnicity, and nativity were recorded on the birth certificate. Odds ratios (ORs) and 95% CIs were estimated using logistic regression. Results: The odds of ASD among grandchildren were higher among grandmothers who were US-born Black (OR = 1.25, 95% CI = 1.20-1.31), foreign-born Black (OR = 1.45, 95% CI = 1.17-1.81), US-born Hispanic (OR = 1.19, 95% CI = 1.14-1.23), and foreign-born Hispanic (OR = 1.22, 95% CI = 1.19-1.26), but not US-born Asian Pacific Islander (API; OR = 0.87, 95% CI = 0.75-1.02), foreign-born API (OR = 0.94, 95% CI = 0.88-1.00), or foreign-born White (OR = 0.90, 95% CI = 0.82-0.99), compared to grandmothers who were US-born White. For ASD with ID, associations were stronger for grandmothers who were US- and foreign-born Black and Hispanic, and positive associations were observed for grandmothers who were foreign-born API. Conclusion: Results suggest that the risk of ASD and ASD with ID differ by grandmother's race, ethnicity, and nativity, with higher odds observed among grandmothers who were Black and Hispanic and with the highest risk observed among grandchildren of grandmothers who were foreign-born.
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