Evidence map›Paper›PMID 40922707›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2025

Abundance of Maternal Mitochondrial Genome Is Dispensable up to the Mitochondrial Genome Activation in Post-Implantation Embryos.

Miki Shavit, Marie Vancová, Jan Jedlicka, Tomáš Bílý, Mushrek Mahrouk, Jan Cendelin, Kateřina Grygarova, Kristýna Popelková, Zdeněk Tůma, Gabriela Pribanova and 2 more

Abstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Abundance of Maternal Mitochondrial Genome Is Dispensable up to the Mitochondrial Genome Activation in Post-Implantation Embryos.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Miki ShavitFaculty of Medicine in Pilsen, Biomedical Center, Charles University, Prague, Czech Republic.
Marie VancováInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice, Czech Republic.
Jan JedlickaFaculty of Medicine in Pilsen, Department of Physiology, Charles University, Pilsen, Czech Republic.
Tomáš BílýInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice, Czech Republic.
Mushrek MahroukFaculty of Medicine in Pilsen, Biomedical Center, Charles University, Prague, Czech Republic.
Jan CendelinFaculty of Medicine in Pilsen, Department of Pathological Physiology, Charles University, Pilsen, Czech Republic.
Kateřina GrygarovaFaculty of Medicine in Pilsen, Biomedical Center, Charles University, Prague, Czech Republic.
Kristýna PopelkováFaculty of Medicine in Pilsen, Biomedical Center, Charles University, Prague, Czech Republic.
Zdeněk TůmaFaculty of Medicine in Pilsen, Biomedical Center, Charles University, Prague, Czech Republic.
Gabriela PribanovaFaculty of Medicine in Pilsen, Biomedical Center, Charles University, Prague, Czech Republic.
Jitka KuncováFaculty of Medicine in Pilsen, Department of Physiology, Charles University, Pilsen, Czech Republic.
Jan NevoralFaculty of Medicine in Pilsen, Biomedical Center, Charles University, Prague, Czech Republic.ORCID https://orcid.org/0000-0002-2048-7325

Funding

European Regional Development Fund - Project "Fighting Infectious Diseases" CZ.02.1.01/0.0/0.0/16_019/0000787Grant Agency of Charles University 254323MED/DIAGMED/IMMU of Charles University SVV 260 773Ministerstvo e a T lov chovy (MMT) 8X23009Ministerstvo e a T lov chovy (MMT) Cooperatio MED/DIAGMinisterstvo e a T lov chovy (MMT) Cooperatio MED/IMMUMinisterstvo e a T lov chovy (MMT) SVV 260 773Ministerstvo kolstv, Ml de e a T lov chovy (MMT) CZ.02.1.01/0.0/0.0/18_046/0016045Ministerstvo kolstv, Ml de e a T lov chovy (MMT) LM2023050Ministry of Education, Youth and Sports of the Czech Republic (MEYS CR) CZ.02.1.01/0.0/0.0/18_046/0016045Ministry of Education, Youth and Sports of the Czech Republic (MEYS CR) LM2023050MSTC in the Danube Region 8X23009Technologick Agentura esk Republiky (Czech Technological Agency) QL24010123Technology Agency of the Czech Republic QL24010123
6 · The paper itself

Abstract

Mitochondria in the egg are suggested to be crucial for the onset of new life. However, there is ambiguous knowledge about the necessity for fertilization and early embryonic development. Therefore, we created a conditional Tfam knockout (Tfam

Indexed as

DNA, MitochondrialEmbryo ImplantationEmbryonic DevelopmentGenome, MitochondrialMitochondriaOocytesAnimalsBlastocystDNA ReplicationEmbryo, MammalianFemaleMaleMiceMice, KnockoutDNA, Mitochondrialembryofertilizationmitochondrialmitochondrionoocytetranscription factor A

Identifiers

PMID40922707
PMCPMC12418054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.