Evidence map›Paper›PMID 40922687›Full record

ArticleGlobal health action2025

Estimated cost-savings from integrated care for HIV, diabetes and hypertension in sub-Saharan Africa: a cost-minimisation analysis.

Gerard Joseph Abou Jaoude, Sokoine Kivuyo, Josephine Birungi, Joseph Okebe, Kaushik Ramaiya, Ivan Namakoola, Simple Ouma, Anupam Garrib, Erik van Widenfelt, Jeffrey Victor Lazarus and 9 more

Abstract read
In one paragraph

Article in Global health action, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Gerard Joseph Abou JaoudeInstitute for Global Health, University College London, London, UK.ORCID 0000-0001-6022-3036
Sokoine KivuyoMuhimbili Centre, National Institute for Medical Research, Dar es Salaam, Tanzania.ORCID 0000-0003-2257-5254
Josephine BirungiThe AIDS Support Organisation, Mulago Hospital Complex, Kampala, Uganda.
Joseph OkebeInstitute for Global Health, University College London, London, UK.ORCID 0000-0001-5466-1611
Kaushik RamaiyaTanzania NCDs Alliance, Dar es Salaam, Tanzania.ORCID 0000-0003-3309-5395
Ivan NamakoolaMedical Research Council/Uganda Virus Research Institute & London School of Hygiene and Tropical Medicine (MRC/UVRI & LSHTM), Uganda Research Unit, Entebbe, Uganda.
Simple OumaThe AIDS Support Organisation, Mulago Hospital Complex, Kampala, Uganda.ORCID 0000-0002-4510-6736
Anupam GarribInstitute for Global Health, University College London, London, UK.ORCID 0000-0003-2305-3749
Erik van WidenfeltInstitute for Global Health, University College London, London, UK.
Jeffrey Victor LazarusBarcelona Institute for Global Health (ISGlobal) Hospital Clínic, University of Barcelona, Barcelona, Spain.ORCID 0000-0001-9618-2299
Gerald MutungiNon-Communicable Diseases Control Programme, Ministry of Health, Kampala, Uganda.
Omary UbuguyuMinistry of Health, United Republic of Tanzania Ministry of Health, Dodoma, Tanzania.
Mina Nakawuka SsaliAIDS Control Programme, Ministry of Health, Kampala, Uganda.
Nelson K SewankamboSchool of Public Health, Makerere University College of Health Sciences, Kampala, Uganda.ORCID 0000-0001-9362-053X
Jolene SkordisInstitute for Global Health, University College London, London, UK.ORCID 0000-0002-8633-0208
Sayoki MfinangaInstitute for Global Health, University College London, London, UK.ORCID 0000-0001-9067-2684
Moffat J NyirendaThe AIDS Support Organisation, Mulago Hospital Complex, Kampala, Uganda.ORCID 0000-0003-2120-4806
Shabbar JaffarInstitute for Global Health, University College London, London, UK.ORCID 0000-0002-9615-1588
Neha BaturaInstitute for Global Health, University College London, London, UK.ORCID 0000-0002-8175-8125

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn a cluster-randomised trial in Uganda and Tanzania, we showed that integrated management, compared with standard vertical care, could achieve a high standard of care for diabetes and hypertension without adversely affecting outcomes for HIV. However, evidence on the value for money of integrated care is needed to inform policy.

objectiveOur economic evaluation aimed to establish the value for money of integrated care compared with vertical care for HIV, diabetes and hypertension.

methodsA societal perspective was adopted, considering provider and patient costs for integrated and standard care in Uganda and Tanzania over one year. Provider costs were estimated for 6714 participants based on five representative health facilities per country. Patient costs were captured via questionnaire from a sub-sample of 2708 participants. Provider costs at scale were estimated using national prevalence and utilisation data. Key inputs were varied in two-way sensitivity analyses.

resultsAmong participants with single conditions, mean provider and patient costs per patient-visit did not differ significantly between integrated and standard care. Among participants with multiple conditions, mean provider and patient costs per patient-visit were, respectively, Int$18.67 (95%CI 10.89-26.45,

conclusionIntegrated care is cost-saving from a societal perspective and should be considered for scale-up in Tanzania, Uganda and similar settings. TRIAL REGISTRATION NUMBER: ISRCTN43896688.

Indexed as

Cost SavingsDelivery of Health Care, IntegratedDiabetes MellitusHIV InfectionsHypertensionAdultCost-Benefit AnalysisFemaleHealth Care CostsHumansMaleMiddle AgedTanzaniaUgandachronic careEconomic evaluationintegrated carenon-communicablerandomised trial

Identifiers

PMID40922687
PMCPMC12422034

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.