Evidence map›Paper›PMID 40922624›Full record

ReviewAdvanced materials (Deerfield Beach, Fla.)2026

Sacrificial Biofabrication for Vascularization: Concept, Materials, Technologies, and Applications.

Jiezhong Shi, Chunyao Wang, Xuan Mei, Ben Zhang, Junxi Wu, Rylie A Green, Yu Shrike Zhang, Wenmiao Shu

Abstract readReview
In one paragraph

Review in Advanced materials (Deerfield Beach, Fla.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
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  5. Article
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiezhong ShiSINOPEC Key Laboratory of Research and Application of Medical and Hygienic Materials, SINOPEC Beijing Research Institute of Chemical Industry Co., Ltd., Beijing, 100013, P. R. China.
Chunyao WangSINOPEC Key Laboratory of Research and Application of Medical and Hygienic Materials, SINOPEC Beijing Research Institute of Chemical Industry Co., Ltd., Beijing, 100013, P. R. China.
Xuan MeiDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.
Ben ZhangSINOPEC Key Laboratory of Research and Application of Medical and Hygienic Materials, SINOPEC Beijing Research Institute of Chemical Industry Co., Ltd., Beijing, 100013, P. R. China.
Junxi WuDepartment of Biomedical Engineering, University of Strathclyde, Glasgow, G4 0NW, UK.
Rylie A GreenDepartment of Bioengineering, Imperial College London, London, SW7 2BX, UK.
Yu Shrike ZhangDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.ORCID 0000-0002-0045-0808
Wenmiao ShuDepartment of Biomedical Engineering, University of Strathclyde, Glasgow, G4 0NW, UK.ORCID 0000-0002-1220-361X

Funding

Brigham Research InstituteChan Zuckerberg Initiative 2024-347836/CZINational Research Foundation of Korea RS-2024-00403376Research and Development project of SINOPEC 223077UKRI-EPSRC EP/M506837/1UKRI-EPSRC EP/X033686/1UKRI-Medical Research Council MR/V029827/1
6 · The paper itself

Abstract

Vasculature plays a crucial role in tissue engineering since it is essential for maintaining tissue viability by efficient nutrient and oxygen exchange as well as waste removal. The creation of biomimetic vascular networks is therefore critical for the development of functional tissue constructs. Sacrificial biofabrication has emerged as an effective method for engineering vascular structures by creating temporary templates that are subsequently removed to form well-defined vascular channels. In this review, the concept of sacrificial biofabrication is introduced and defined, with a focus on vascularization. Then, a comprehensive overview of the commonly used sacrificial materials based on different types of external stimuli is provided, and the classification and design principles of surrounding materials are briefly introduced. Additionally, various fabrication technologies employed to process sacrificial materials are summarized, and the diverse applications of sacrificial biofabrication in disease models and regenerative medicine are discussed. Finally, the current challenges are highlighted, and the future perspectives for advancing sacrificial biofabrication are explored to address the demand for vasculature manufacturing.

Indexed as

Biocompatible MaterialsNeovascularization, PhysiologicTissue EngineeringAnimalsHumansRegenerative MedicineTissue ScaffoldsBiocompatible Materials3D printingbiomedical engineeringhydrogelsacrificial biofabricationvasculature

Identifiers

PMID40922624
PMCPMC12783884

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.