ArticleThe Permanente journal2025
Impact of Clinical Pharmacy Team Intervention on Naloxone Fills in Patients on ChroCnic Opioid Therapy.
Article in The Permanente journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Patient Insights to Improve Naloxone Access and Decision Support.The Permanente journal · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOpioids are highly effective for pain management but carry risks. Naloxone quickly reverses opioid overdoses by blocking opioid receptors in the brain. Despite its effectiveness, naloxone remains underutilized. Kaiser Permanente created the Interregional Pharmacy Opioid Use Improvement Group to support safe opioid prescribing and increase appropriate naloxone prescribing.
methodsThis retrospective study included Kaiser Permanente Georgia members who were 18 years or older and filling chronic opioid therapy of ≥ 50 morphine milligram equivalents (MME) averaged over the previous 90 days. The primary objective was to compare the number of patients who filled a naloxone prescription within the last 24 months as of March 31, 2023 (preintervention) vs as of December 31, 2023 (postintervention). The secondary outcome was to compare the naloxone fill rates based on intervention type.
resultsAs of March 31, 2023, 122 out of 399 patients (30.6%) had filled naloxone prescriptions compared to 241 out of 356 patients (67.7%) as of December 31, 2023 (30.6% vs 67.7%;
conclusionsPharmacy-led interventions, particularly telephone outreach, were effective at improving naloxone fill rates in patients on chronic opioid therapy of ≥ 50 morphine milligram equivalents per day. Voicemails had a lower fill rate, highlighting the importance of direct interaction in improving patient outcomes.
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