Evidence map›Paper›PMID 40922108›Full record

ArticleActa paediatrica (Oslo, Norway : 1992)2026

Amplitude-Integrated Electroencephalography Signals, Abnormal General Movements and Later Motor Outcome in Preterm Infants.

Marlene Hammerl, Anna Posod, Maria Sappler, Christina Schreiner, Nina Gande, Vera Neubauer, Ursula Kiechl-Kohlendorfer, Elke Griesmaier

Abstract read
In one paragraph

Article in Acta paediatrica (Oslo, Norway : 1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marlene HammerlDepartment of Pediatrics II (Neonatology), Medical University of Innsbruck, Innsbruck, Austria.
Anna PosodDepartment of Pediatrics II (Neonatology), Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0003-1008-3375
Maria SapplerDepartment of Pediatrics II (Neonatology), Medical University of Innsbruck, Innsbruck, Austria.
Christina SchreinerDepartment of Pediatrics II (Neonatology), Medical University of Innsbruck, Innsbruck, Austria.
Nina GandeDepartment of Pediatrics II (Neonatology), Medical University of Innsbruck, Innsbruck, Austria.
Vera NeubauerDepartment of Pediatrics II (Neonatology), Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0001-6638-8624
Ursula Kiechl-KohlendorferDepartment of Pediatrics II (Neonatology), Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0003-0433-6196
Elke GriesmaierDepartment of Pediatrics II (Neonatology), Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0002-9269-5756

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the relationship between amplitude-integrated electroencephalography (aEEG), general movement assessment (GMA) and later motor outcome in preterm infants.

methodsThis retrospective study analysed data from 274 very preterm infants born at Innsbruck Medical University Hospital. aEEG was performed within 72 h of birth and weekly for the first month. GMA was conducted at 34, 40 and 52 weeks postmenstrual age. Motor outcome was assessed at 2 years. Statistical analyses included comparative tests, multivariate logistic regression and ROC curves.

resultsSignificant differences in aEEG scores were observed between infants with normal and abnormal GMs. After adjusting for neonatal characteristics, only day 1 aEEG remained significantly associated with general movements (GMs) at term and post-term. At 2 years, psychomotor outcome was significantly delayed in infants with abnormal GMA at term and post-term.

conclusionsThis study underscores the importance of integrating aEEG and GMA in preterm infants. Our findings should be interpreted as a proof-of-concept, illustrating the feasibility of integrating aEEG with GMA for a comprehensive evaluation of early neurodevelopment. Future research should investigate potential synergistic effects of diagnostic tools to identify infants at risk for neurological injury and developmental delay with the aim to assess the effect of early interventions.

Indexed as

ElectroencephalographyInfant, PrematureFemaleHumansInfant, NewbornMaleRetrospective Studiesamplitude‐integrated electroencephalographybrain maturationgeneral movementsmotor outcomepreterm brain functionpreterm infant

Identifiers

PMID40922108
PMCPMC12687719

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