Evidence map›Paper›PMID 40922021›Full record

Trial reportBMC anesthesiology2025

Effect of virtual reality on perioperative anxiety, stress and pain in total hip arthroplasty: a randomized controlled trial.

Saad Ahmed Moharam, Mohammed Said ElSharkawy, Ahmed Mohamed ELkashef, Mohamed Abdelhamed Romeih, Ahmed Osama Abd Rab El Rasool, Mostafa Mohamed Shaheen

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06088069 (Effect of Virtual Reality on Perioperative Anxiety, Stress and Pain in Total Hip Arthroplasty), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06088069 nacompletednot on this map

Effect of Virtual Reality on Perioperative Anxiety, Stress and Pain in Total Hip Arthroplasty: a Randomized Controlled Trial

TypeinterventionalSponsorTanta UniversityRan2023 to 2024Enrolled50ConditionsVirtual Reality, Total Hip Arthroplasty, Anxiety, StressArmsVirtual reality
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Saad Ahmed MoharamFaculty of Medicine, Anesthesiology, Surgical Intensive Care and Pain Medicine Department, Tanta University, Tanta, El Gharbia, 31511, Egypt. saad.moharam@med.tanta.edu.eg.ORCID http://orcid.org/0000-0002-1364-4679
Mohammed Said ElSharkawyFaculty of Medicine, Anesthesiology, Surgical Intensive Care and Pain Medicine Department, Tanta University, Tanta, El Gharbia, 31511, Egypt.
Ahmed Mohamed ELkashefFaculty of Medicine, Anesthesiology, Surgical Intensive Care and Pain Medicine Department, Tanta University, Tanta, El Gharbia, 31511, Egypt.
Mohamed Abdelhamed RomeihFaculty of Medicine, Orthopedic Surgery Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
Ahmed Osama Abd Rab El RasoolFaculty of Medicine, Neuropsychiatry Department, Tanta University, Tanta, Egypt.
Mostafa Mohamed ShaheenFaculty of Medicine, Anesthesiology, Surgical Intensive Care and Pain Medicine Department, Tanta University, Tanta, El Gharbia, 31511, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVirtual reality (VR) has shown promise as a nonpharmacological alternative to pharmaceutical pain relievers and anxiety medications in clinical trials by decreasing pain and anxiety in orthopedic surgeries. The aim of the study was to evaluate the impact of VR on these outcomes in individuals undergoing total hip arthroplasty (THA).

methodsThis randomized, controlled, open-label research included 50 participants planned for THA with spinal anesthesia (SA). Patients were allocated equally to group VR: patients were immersed in a peaceful natural environment with soft music preoperatively and intraoperatively, and group C did not receive VR.

resultsThe STAI-S for anxiety and PSS-10 scores for stress were significantly lower in group VR before SA and immediately postoperatively (P < 0.05). Hemodynamics at 5 min, 30 min, and 60 min, pain scores at 4 h and 6 h, 24 h pethidine consumption, haloperidol dose, and cortisol level at 6 h postoperative were decrease in group VR in comparision to group C (P < 0.05). Time to first analgesia request and satisfaction level were higher in group VR in comparision to group C (P < 0.05).

conclusionsVR can reduce perioperative anxiety, stress, pain, and opioid requirements, and improve satisfaction in THA patients.

trial registrationThe trial was registered https://clinicaltrials.gov/study/NCT06088069?id=NCT06088069&rank=1((ID:NCT06088069 , Principal investigator: (SAAD AHMED MOHARAM, Date of registration: 18-10-2023).

Indexed as

AnxietyArthroplasty, Replacement, HipPostoperative PainStress, PsychologicalVirtual RealityAgedAnalgesics, OpioidAnesthesia, SpinalFemaleHumansMaleMiddle AgedPain MeasurementAnalgesics, OpioidAnxietyPainStressTotal hip arthroplastyVirtual reality

Identifiers

PMID40922021
PMCPMC12418640

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.