Evidence map›Paper›PMID 40921906›Full record

ArticleIntensive care medicine experimental2025

Regional venous-to-arterial carbon dioxide pressure and content differences during endotoxemic shock: influence of hydrogen ion accumulation vs. Haldane effect.

Gustavo A Ospina-Tascón, Daniel De Backer, José L Aldana, Alberto F García Marín, Luis E Calderón, Julián Chica, Gustavo García-Gallardo, Nicolás Orozco, Jihad Mallat

Abstract read
In one paragraph

Article in Intensive care medicine experimental, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gustavo A Ospina-TascónDepartment of Intensive Care, Fundación Valle del Lili, Cali, Colombia. gusospin@gmail.com.ORCID http://orcid.org/0000-0001-9370-3298
Daniel De BackerIntensive Care Department. CHIREC Hospitals, Université Libre de Bruxelles, Brussels, Belgium.
José L AldanaDepartment of Intensive Care, Fundación Valle del Lili, Cali, Colombia.
Alberto F García MarínDepartment of Intensive Care, Fundación Valle del Lili, Cali, Colombia.
Luis E CalderónDepartment of Intensive Care, Fundación Valle del Lili, Cali, Colombia.
Julián ChicaDepartment of Intensive Care, Fundación Valle del Lili, Cali, Colombia.
Gustavo García-GallardoDepartment of Intensive Care, Fundación Valle del Lili, Cali, Colombia.
Nicolás OrozcoDepartment of Intensive Care, Fundación Valle del Lili, Cali, Colombia.
Jihad MallatCritical Care Division, Integrated Hospital Care Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between carbon dioxide pressures (PCO

methodsShock was induced by an escalating dose of lipopolysaccharide in 12 female Landrace pigs. Norepinephrine was then started to maintain mean arterial pressure ≥ 75 mmHg, while successive fluid boluses were administered targeting arterial lactate < 2.0 mmol·L

resultsVariations in ∆-[|∆PCO

conclusionsRegional splanchnic PCO

Indexed as

CO2 contentDouglas equationHaldane effectPCO2:CCO2 dissociation curvePCO2 gaps

Identifiers

PMID40921906
PMCPMC12417345

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