ArticleClinical oral investigations2025
Association between vitamin K intake and periodontitis in American elderly population: a cross-sectional analysis of NHANES data.
Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Vitamins and Vitamin-like Compounds in Severe Canine Periodontal Disease: A Prospective Exploratory Cross-Sectional Pilot Study.Veterinary sciences · 2026Article
- Association Between Glyco-Lipid Seven-Factor Index, a Novel Composite Glyco-Lipid Index, and Periodontitis: A Cross-Sectional Study.International dental journal · 2026Article
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9 authors.
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Abstract
backgroundAn increasing amount of data has been acquired on the close relationship between Vitamin K intake and the progression of periodontitis. The purpose of this study was to estimate whether Vitamin K intake is associated with periodontitis among older adults in America using information from the National Health and Nutrition Examination Survey (NHANES) database.
methodsA cross-sectional analysis of data on periodontal indices and vitamin K intake among American adults aged 60 years and older in the 2009-2014 NHANES database was extracted. Periodontitis was defined according to CDC/AAP criteria, classification of periodontitis and severity of periodontitis according to the degree and amount of attachment loss in the interproximal site, and vitamin K intake was categorized using optimal cutoff value. Univariate and multivariate logistic regression analyses were used to investigate the association between vitamin K intake and the risk of periodontitis.
resultsBased on the information analysis of 2303 participants who met the inclusion criteria, the risk of periodontitis was lower in the elderly population with higher vitamin K intake. Especially, a statistically significant reduction in the prevalence of periodontitis was observed in elderly populations with vitamin K intake greater than 89.51 mg/d (OR = 0.648,95%Cl = 0.502-0.837, P value = 0.001) compared to those with vitamin K intake less than 89.51 mg/d. Subgroup analyses revealed that this association was more prominent in elderly people aged 60-69 years and 70-79 years, the female/male population, the Non-Hispanic White population, those with a poverty index of 1.3-3.5, education level over high school grad/GED, non-smokers, 1-5 drinks/month, non-alcohol drinkers, overweight, normal blood pressure and without diabetes.
conclusionOur research found a strong relationship between vitamin K intake and periodontitis among elderly people in the United States, suggesting vitamin K intake is a possible risk factor and may be a novel idea for the diagnosis and treatment of periodontitis.
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