Evidence map›Paper›PMID 40921880›Full record

ArticleSkeletal radiology2026

Assessing the ability of large language models to simplify lumbar spine imaging reports into patient-facing text: a pilot study of GPT-4.

Rushmin Khazanchi, Austin R Chen, Parth Desai, Daniel Herrera, Jacob R Staub, Matthew A Follett, Mykhaylo Krushelnytskyy, Hanna Kemeny, Wellington K Hsu, Alpesh A Patel and 1 more

Abstract read
In one paragraph

Article in Skeletal radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rushmin KhazanchiFeinberg School of Medicine, Northwestern University, 676 N. St. Clair Street, Suite 1350, Chicago, IL, 60611, USA. rushmin.khazanchi@northwestern.edu.
Austin R ChenFeinberg School of Medicine, Northwestern University, 676 N. St. Clair Street, Suite 1350, Chicago, IL, 60611, USA.
Parth DesaiDepartment of Orthopaedic Surgery, Northwestern University, Chicago, IL, USA.
Daniel HerreraFeinberg School of Medicine, Northwestern University, 676 N. St. Clair Street, Suite 1350, Chicago, IL, 60611, USA.
Jacob R StaubFeinberg School of Medicine, Northwestern University, 676 N. St. Clair Street, Suite 1350, Chicago, IL, 60611, USA.
Matthew A FollettDepartment of Orthopaedic Surgery, Northwestern University, Chicago, IL, USA.
Mykhaylo KrushelnytskyyDepartment of Neurological Surgery, Northwestern University, Chicago, IL, USA.
Hanna KemenyDepartment of Neurological Surgery, Northwestern University, Chicago, IL, USA.
Wellington K HsuDepartment of Orthopaedic Surgery, Northwestern University, Chicago, IL, USA.
Alpesh A PatelDepartment of Orthopaedic Surgery, Northwestern University, Chicago, IL, USA.
Srikanth N DiviDepartment of Orthopaedic Surgery, Northwestern University, Chicago, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the ability of large language models (LLMs) to accurately simplify lumbar spine magnetic resonance imaging (MRI) reports. MATERIALS AND

methodsPatients who underwent lumbar decompression and/or fusion surgery in 2022 at one tertiary academic medical center were queried using appropriate CPT codes. We then identified all patients with a preoperative ICD diagnosis of lumbar spondylolisthesis and extracted the latest preoperative spine MRI radiology report text. The GPT-4 API was deployed on deidentified reports with a prompt to produce translations and evaluated for accuracy and readability. An enhanced GPT prompt was constructed using high-scoring reports and evaluated on low-scoring reports.

resultsOf 93 included reports, GPT effectively reduced the average reading level (11.47 versus 8.50, p < 0.001). While most reports had no accuracy issues, 34% of translations omitted at least one clinically relevant piece of information, while 6% produced a clinically significant inaccuracy in the translation. An enhanced prompt model using high scoring reports-maintained reading level while significantly improving omission rate (p < 0.0001). However, even in the enhanced prompt model, GPT made several errors regarding location of stenosis, description of prior spine surgery, and description of other spine pathologies.

conclusionGPT-4 effectively simplifies the reading level of lumbar spine MRI reports. The model tends to omit key information in its translations, which can be mitigated with enhanced prompting. Further validation in the domain of spine radiology needs to be performed to facilitate clinical integration.

Indexed as

Lumbar VertebraeMagnetic Resonance ImagingRadiology Information SystemsSpondylolisthesisDecompression, SurgicalFemaleHumansLarge Language ModelsMalePilot ProjectsRetrospective StudiesSpinal FusionArtificial intelligenceGPTLarge language modelsLumbar spineMRIRadiologyReading level

Identifiers

PMID40921880
PMCPMC12743105

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.