Evidence map›Paper›PMID 40921863›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2025

Is trabecular bone score associated with appendicular lean mass?

Lora M Giangregorio, Mackenzie Ryann Alexiuk, Navdeep Tangri, Didier Hans, William D Leslie

Abstract read
PubMed Publisher
In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lora M GiangregorioUniversity of Waterloo and Schlegel-UW Research Institute for Aging, Waterloo, Canada. lora.giangregorio@uwaterloo.ca.ORCID http://orcid.org/0000-0002-3739-1805
Mackenzie Ryann AlexiukChronic Disease Innovation Centre, Winnipeg, MB, Canada.
Navdeep TangriChronic Disease Innovation Centre, Winnipeg, MB, Canada.
Didier HansInterdisciplinary Center of Bone Diseases, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
William D LeslieUniversity of Manitoba, Winnipeg, MB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among individuals aged ≥ 40 years old, we found that after controlling for age, sex, FMI, and tissue thickness, an increase of 1kg/m

backgroundTrabecular bone score (TBS) has been shown to be an independent risk factor for fracture. Muscle pulling on bone is hypothesized to be a mechanical stimulus for osteogenesis. Our aim was to explore whether TBS is associated with appendicular lean mass index (ALMI, appendicular lean mass divided by height squared, units kg/m2).

methodsWe used visit data from individuals aged 40 years and older in the Manitoba DXA Registry (February 1999-March 2016). ALMI, total body lean mass index (LMI) and total body fat mass index (FMI) were estimated from weight, sex, and percent fat from spine and hip DXA (all R

resultsAmong 60,196 individuals (90% female), descriptive statistics as mean (SD) were: TBS 1.245 (0.122), BMI 26.4 kg/m

conclusionsALMI was associated with TBS after controlling for age, sex, FMI, and abdominal tissue thickness.

Indexed as

Body CompositionBone DensityCancellous BoneAbsorptiometry, PhotonAdultAgedAged, 80 and overAnthropometryBody Mass IndexCross-Sectional StudiesFemaleHumansLumbar VertebraeMaleMiddle AgedRegistriesBody compositionBone densitometryFractureLean massOsteoporosisSarcopeniaTrabecular bone score

Identifiers

PMID40921863

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.