Evidence map›Paper›PMID 40921836›Full record

ArticleSurgical endoscopy2025

Zipper endoscopic full-thickness resection: a pilot study in subepithelial tumor management (with video).

Jie He, Peirong Xu, Hua Gao, Ziyu Wang, Zuqiang Liu, Li Wang, Weifeng Chen, Quanlin Li, Pinghong Zhou, Hao Hu

Abstract readVideo-Audio Media
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jie He *Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Peirong Xu *Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Hua Gao *Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Ziyu WangEndoscopy Center, Minhang Hospital, Fudan University, Shanghai, China.
Zuqiang LiuEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Li WangEndoscopy Center, Shanghai Geriatric Medical Center, Shanghai, China.
Weifeng ChenEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Quanlin LiEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Pinghong ZhouEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China. zhou.pinghong@zs-hospital.sh.cn.ORCID http://orcid.org/0000-0002-5434-0540
Hao HuEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China. hu.hao1@zs-hospital.sh.cn.

Funding

National Key R&D Program 2022YFC2505100National Key R&D Program 2022YFC2505105National Natural Science Foundation of China 81900548National Natural Science Foundation of China 82370546Science and Technology Commission of Shanghai Municipality 22015831400Science and Technology Commission of Shanghai Municipality 22Y11907500Science and Technology Commission of Shanghai Municipality 23ZR1453100Youth Foundation of Shanghai Geriatric Medical Center YQ2024-010
6 · The paper itself

Abstract

BACKGROUND AND

aimsTraditional endoscopic full-thickness resection (EFTR) involves complete removal of the lesion followed by defect closure. The separated resection and closure technique results in mucosal eversion and misalignment of the muscularis propria layers, making reliable closure difficult. Here, we developed an innovative "cut-and-seal-as-you-go" technique, "Zipper-EFTR" and evaluated the feasibility and safety of the new technique. MATERIALS AND

methodsWe prospectively enrolled 15 patients with gastric subepithelial tumors resected by Zipper-EFTR. The primary outcome was the technical success rate. Secondary outcomes included the incidence of adverse events, procedure duration, and length of postprocedural hospital stay.

resultsThe median maximum size of the lesions was 1.2 cm (range, 0.6-2.0), with 10 lesions in the fundus and 5 in the corpus. All lesions were successfully resected by Zipper-EFTR, and no patient developed fever or severe abdominal pain or other serious adverse events, such as perforation, bleeding, and abdominal abscess. The en bloc resection rate was 100% and the median procedure duration was 25 min (range, 20 -60). All patients were discharged safely with a median length of postprocedural hospital stay of 3 days (range, 2-4).

conclusionThe Zipper-EFTR is a simple, safe, and easy-to-use technique for gastric subepithelial tumors.

Indexed as

GastroscopyStomach NeoplasmsAdultAgedFeasibility StudiesFemaleHumansLength of StayMaleMiddle AgedOperative TimePilot ProjectsProspective StudiesTreatment OutcomeClosureEndoscopic resectionSubepithelial tumorsSuturing

Identifiers

PMID40921836

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.