SynthesisSurgical endoscopy2025
Laparoscopic endoscopic cooperative surgery versus laparoscopic segmental resection for the treatment of endoscopically unresectable colorectal polyps: a systematic review and meta-analysis.
Synthesis in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Direct access robotic excision (DARE): a novel colonoscopy-assisted approach for full-thickness resection of complex colonic polyps.Surgical endoscopy · 2026Article
- Case Report: Laparoscopic-endoscopic cooperative full-thickness resection for recurrent transverse colon cancer after rectal cancer surgery: a case report with video.Frontiers in oncology · 2026Article
- Laparoscopic and endoscopic cooperative surgery in gastrointestinal tumors: current applications, oncologic considerations, and future directions.Frontiers in oncology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundLaparoscopic segmental resection (LSR) is a common treatment modality for endoscopically unresectable colorectal polyps. Laparoscopic endoscopic cooperative surgery (LECS) has emerged as a promising alternative, yet current evidence of its efficacy remains limited.
objectivesThis meta-analysis aims to compare the therapeutic outcomes of LECS versus LSR for endoscopically unresectable colorectal polyps and to provide robust evidence for clinical practice.
methodsThis meta-analysis was prospectively registered on the PROSPERO website. We systematically searched PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wanfang Data, VIP, and CBM for randomized controlled trials (RCTs) and observational studies from database inception to May 16, 2025. Data analysis was conducted using Review Manager 5.4 and Stata 18 software. Certainty of evidence was assessed using Grading of Recommendations Assessment, Development and Evaluation (GRADE).
resultsA total of 13 studies involving 715 patients were included in this study. Meta-analysis results showed that the LECS group had a significantly shorter length of hospital stay (MD: -2.89 days, 95% CI: -3.43 to -2.34, 13 studies, 715 patients), shorter operation time (MD: -41.62 min, 95% CI: -56.96 to -26.28, 12 studies, 593 patients), fewer postoperative overall complications (OR: 0.29, 95% CI: 0.17 to 0.49, 9 studies, 513 patients), and lower estimated blood loss (MD: - 26.12 mL, 95% CI: -37.07 to -15.17, 8 studies, 435 patients) when compared to the LSR group.
conclusionsLECS demonstrates superior short-term outcomes compared to LSR and should be considered a preeminent alternative for endoscopically unresectable colorectal polyps. However, long-term efficacy remains to be confirmed by well-designed, high-quality trials.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.