Evidence map›Paper›PMID 40921741›Full record

SynthesisProstate cancer and prostatic diseases2026

Outcomes of robot-assisted radical prostatectomy with novel robotic platforms vs da Vinci multiport systems: a systematic review and network meta-analysis.

Francesco Chierigo, Giuseppe Fallara, Massimiliano Depalma, Marco Tozzi, Alberto Quistini, Roberto Bianchi, Martina Maggi, Guglielmo Mantica, Cosimo De Nunzio, Rocco Damiano and 7 more

Abstract readSystematic ReviewMeta-AnalysisComparative Study
PubMed Publisher
In one paragraph

Synthesis in Prostate cancer and prostatic diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. da VinciBMC surgery · 2026
    Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Francesco ChierigoDepartment of Urology, Department of Health Science, University of Milan, ASST Santi Paolo e Carlo, Milan, Italy. francesco.chierigo@gmail.com.ORCID http://orcid.org/0000-0001-7357-0758
Giuseppe FallaraDepartment of Urology, Department of Health Science, University of Milan, ASST Santi Paolo e Carlo, Milan, Italy.ORCID http://orcid.org/0000-0001-7872-2650
Massimiliano DepalmaDepartment of Urology, Department of Health Science, University of Milan, ASST Santi Paolo e Carlo, Milan, Italy.
Marco TozziDepartment of Urology, Department of Health Science, University of Milan, ASST Santi Paolo e Carlo, Milan, Italy.
Alberto QuistiniDepartment of Urology, Department of Health Science, University of Milan, ASST Santi Paolo e Carlo, Milan, Italy.ORCID http://orcid.org/0009-0001-7188-2122
Roberto BianchiDepartment of Urology, Department of Health Science, University of Milan, ASST Santi Paolo e Carlo, Milan, Italy.
Martina MaggiDepartment of Urology, Department of Health Science, University of Milan, ASST Santi Paolo e Carlo, Milan, Italy.ORCID http://orcid.org/0000-0003-4672-850X
Guglielmo ManticaDepartment of Surgical and Diagnostic Integrated Sciences (DISC), University of Genoa; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Cosimo De NunzioDepartment of Urology, Sant'Andrea Hospital, Sapienza University, Rome, Italy.ORCID http://orcid.org/0000-0002-2190-512X
Rocco DamianoDepartment of Urology, Magna Graecia University, Catanzaro, Italy.
Alessandro VecciaDepartment of Urology, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.ORCID http://orcid.org/0000-0001-5947-3206
Alessandro AntonelliDepartment of Urology, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.ORCID http://orcid.org/0000-0002-7455-8803
Francesco PorpigliaDepartment of Oncology, Division of Urology, San Luigi Gonzaga Hospital, Turin, Italy.
Pierre KarakiewiczCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montreal Health Center, Montreal, QC, Canada.
Riccardo AutorinoDepartment of Urology, Rush University Medical Center, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-7045-7725
Bernardo Rocco *Department of Urology, IRCCS A. Gemelli University Polyclinic Foundation, Sacred Heart Catholic University, Rome, Italy.
Matteo Ferro *Department of Urology, Department of Health Science, University of Milan, ASST Santi Paolo e Carlo, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe introduction of novel robotic platforms has expanded surgical options for robot-assisted radical prostatectomy (RARP). However, comparative outcomes with da Vinci multiport (MP) system remain unclear. This systematic review and network meta-analysis aimed to compare perioperative, early oncological, and functional outcomes of RARP performed with novel robotic platforms versus the da Vinci MP system.

methodsA systematic literature search was conducted in PubMed, Scopus, and Embase (updated December 22, 2024) following PRISMA guidelines. Eligible studies compared RARP performed with alternative robotic platforms versus da Vinci MP, reporting perioperative, oncological, or functional outcomes. A network meta-analysis was conducted using a random-effects model. Outcomes were expressed as mean differences for continuous variables and odds ratios (OR) for dichotomous variables, with 95% confidence intervals (CI).

resultsThirty-three studies for a total of 5987 patients were included. Compared to da Vinci MP, da Vinci SP had lower odds of lymph node dissection (OR 0.39, 95% CI 0.26-0.61) and nerve-sparing (OR 0.11, 95% CI 0.02-0.61) but was associated with shorter catheterization (-1.18 days, 95% CI -2.05 to -0.31) and hospital stay (-0.68 days, 95% CI -1.05 to -0.31). Versius, KangDuo, and SHURUI SP had significantly longer operative times (MD 74.00, 95% CI 42.49-105.51; MD 53.96, 95% CI 18.26-89.67; MD 103.88, 95% CI 69.99-137.78, respectively). Hugo RAS had higher intraoperative malfunction rates (OR 6.53, 95% CI 2.17-19.63). Positive surgical margin rates were lower for da Vinci SP (OR 0.70, 95% CI 0.53-0.92) but higher with the perineal approach (OR 6.30, 95% CI 1.53-25.94). PSA persistence, biochemical recurrence, continence and erectile function rates were comparable across platforms.

conclusionThis is the first network meta-analysis comparing robotic platforms for RARP. While perioperative differences exist, oncological and functional outcomes appear comparable. Future studies should address learning curve effects, cost-effectiveness, and long-term functional outcomes to optimize robotic platform selection.

Indexed as

ProstatectomyProstatic NeoplasmsRobotic Surgical ProceduresHumansMaleNetwork Meta-Analysis as TopicPostoperative ComplicationsTreatment Outcome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.