Evidence map›Paper›PMID 40921737›Full record

ArticleNature communications2025

An electrochemiluminescence device powered by streaming potential for the detection of amines in flowing solution.

Rintaro Suzuki, Suguru Iwai, Ryota Kirino, Kosuke Sato, Mariko Konishi, George Hasegawa, Norio Ishizuka, Kimihiro Matsukawa, Kazuo Tanaka, Elena Villani and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rintaro Suzuki *Department of Chemical Science and Engineering, School of Materials and Chemical Technology, Institute of Science Tokyo, Nagatsuta-cho, Midori-ku, Yokohama, Japan.
Suguru Iwai *Department of Chemical Science and Engineering, School of Materials and Chemical Technology, Institute of Science Tokyo, Nagatsuta-cho, Midori-ku, Yokohama, Japan.ORCID http://orcid.org/0000-0002-2917-2856
Ryota Kirino *Department of Chemical Science and Engineering, School of Materials and Chemical Technology, Institute of Science Tokyo, Nagatsuta-cho, Midori-ku, Yokohama, Japan.
Kosuke SatoDepartment of Chemical Science and Engineering, School of Materials and Chemical Technology, Institute of Science Tokyo, Nagatsuta-cho, Midori-ku, Yokohama, Japan.
Mariko KonishiDepartment of Chemical Science and Engineering, School of Materials and Chemical Technology, Institute of Science Tokyo, Nagatsuta-cho, Midori-ku, Yokohama, Japan.
George HasegawaInstitute of Materials and Systems for Sustainability, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan.ORCID http://orcid.org/0000-0003-4546-5197
Norio IshizukaEmaus Kyoto Inc., Nishida-cho, Saiin, Ukyo-ku, Kyoto, Japan.
Kimihiro MatsukawaMaterials Innovation Lab, Kyoto Institute of Technology, Goshokaido-cho, Matsugasaki, Sakyo-ku, Kyoto, Japan.
Kazuo TanakaDepartment of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, Japan.ORCID http://orcid.org/0000-0001-6571-7086
Elena VillaniDepartment of Chemical Science and Engineering, School of Materials and Chemical Technology, Institute of Science Tokyo, Nagatsuta-cho, Midori-ku, Yokohama, Japan. villani.e@mct.isct.ac.jp.ORCID http://orcid.org/0000-0001-6661-8143
Shinsuke InagiDepartment of Chemical Science and Engineering, School of Materials and Chemical Technology, Institute of Science Tokyo, Nagatsuta-cho, Midori-ku, Yokohama, Japan. inagi@cap.mac.titech.ac.jp.ORCID http://orcid.org/0000-0002-9867-1210

Funding

MEXT | Japan Science and Technology Agency (JST) JPMJFR211GMEXT | Japan Society for the Promotion of Science (JSPS) JP22K14708Ministry of Education, Culture, Sports, Science and Technology (MEXT) JP23H04914Tokyo Institute of Technology (Tokyo Tech) Support for Tokyo Tech Advanced Researchers
6 · The paper itself

Abstract

The research and implementation of portable and low-cost analytical devices that possess high reproducibility and ease of operation is still a challenging task, and a growing field of importance, within the analytical research. Herein, we report the concept, design and optimization of a microfluidic device based on electrochemiluminescence (ECL) detection that can be potentially operated without electricity for analytical purposes. The device functions exploiting the concept of streaming potential-driven bipolar electrochemistry, where a potential difference, generated from the flow of an electrolyte through a microchannel under the influence of a pressure gradient, is the driving force for redox reactions. To our purpose, we employ such a device to drive the ECL reaction of an organic chromophore deposited onto the electrode surface by simply flowing an electrolytic solution containing a coreactant into the microfluidic system, and we successively apply such device for the detection of amines in water. Our device shows high reproducibility and satisfactory detection limits for tri-n-propylamine, demonstrating an original, and up to now unexplored, concept of energy saving microfluidic systems with integrated ECL detection.

Identifiers

PMID40921737
PMCPMC12417550

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.